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Biomedical subjects

V E Kondratov

Publications and source records attributed to V E Kondratov.

3 recordsLinked to original sources

[Microfluorometric study of pH in frog nerves at rest and during rhythmic stimulation].

With the use of microspectrofluorimetry the pH-dynamics in the frog nerve at rest and during rhythmic excitation was investigated. Rhythmic excitation results in an increase of hydrogen ion concentration in the nerve fibres. Metabolic and ion channel inhibitors affect intracellular pH changes. The results obtained suggest different role of various transport systems (sodium pump and ion channels) in the regulation of pH at rest and during rhythmic excitation.

Animals↗

[Proton transport during nerve stimulation].

A decrease of external pH during rhythmic excitation of the nerve of frog and squid was investigated. The level of pH was dependent on frequency excitation, concentration of sodium potassium and hydrogen ions was changed after ouabain, 2,4-dinitrophenol, tetraethylammonium and tetrodotoxin effect. The mechanism of proton transport was discussed in relation to Na-channel function.

Animals↗