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Biomedical subjects

V E Loginskiĭ

Publications and source records attributed to V E Loginskiĭ.

At least 19 recordsLinked to original sources

[Circulating immune complexes and the immune system in hemorrhagic vasculitis].

The paper is concerned with the results of studying the concentration of circulating immune complexes and immune system (the number of lymphocyte populations and subpopulations in the peripheral blood, the level of serum immunoglobulins) in 45 patients aged 10 to 72 years with hemorrhagic vasculitis depending on the disease pattern and course before and after the treatment. The patients suffering from hemorrhagic vasculitis manifested appreciable changes in humoral immunity and negligible derangement of cellular immunity associated with dramatic enhancement of complex formation. The intensity of the alterations was discovered to be dependent on the pattern and course of the disease.

Adolescent

[Immune disorders in hemophiliac patients].

Hemophiliac patients develop disorders of the immune status as a result of transfusion therapy: a decrease in the number of T-lymphocytes and the ratio T-helpers/T-suppressors resulting from a decrease in the number of T-helpers, enhancement of immunoglobulinogenesis, and an increase in the level of circulating immune complexes. A degree of the above changes depends on a dose and period of the use of antihemophilic drugs. Hemophiliac patients require immunological monitoring, clinical substantiation of doses and a prolonged period of administration of blood preparations.

Acute Disease

[Blood serum immunoglobulins in lymphogranulomatosis and other malignant lymphomas].

Under examination were the levels of serum immunoglobulins G, A, M, and D in 25 patients with lymphogranulomatosis and in 22 patients with nonlymphogranulomatous malignant lymphomas. A reliable increase in IgG concentration was found in both groups, but it was more pronounced in cases with malignant lymphomas. The IgA and IgD level also tends to rise but somewhat more sharply in malignant lymphomas. The level of IgM in lymphogranulomatosis patients was not significantly changed, while in nonlymphogranulomatous malignant lymphomas it was raised a little.

Female