PubMed Health⌕ Search

Biomedical subjects

V E Panfilov

Publications and source records attributed to V E Panfilov.

6 recordsLinked to original sources

Human adaptation to simulated gravitational fields.

We present the resuIts of manned studies in which test subjects were exposed to simulated zero g (water immersion or head-down tilt at -6 degrees) and head-to-feet acceleration. The findings give evidence that humans have different individual tolerances to an acceleration of +3 Gz after exposure to zero g, whether simulated by immersion or by head-down tilt. The paper discusses the role of functional relationship between water balance and cardiac output in the establishment of adaptive reactions to simulated zero g.

Acceleration↗

Human adaptation to simulated gravitational fields.

We present the results of manned studies in which test subjects were exposed to simulated zero g (water immersion or head-down tilt at -6 degrees) and head-to-feet acceleration. The findings give evidence that humans have different individual tolerances to an acceleration of +3 Gz after exposure to zero g, whether simulated by immersion or by head-down tilt. The paper discusses the functional relationship between water balance and cardiac output in the establishment of adaptive reactions to simulated zero g.

Adaptation, Physiological↗

Physiological reactions during acute adaptation to reduced gravity.

Experiments were carried out on healthy volunteers exposed to a 7-day water immersion. The subjects were kept dry by use of a water proof, highly elastic cloth. During the experiment different cardiovascular, fluid-electrolyte and biochemical parameters were recorded. During the 7-day immersion, physiological parameters changed on a phasic basis. An acute period of adaptation began within the first minutes of immersion and ended by the third day. Later some of the parameters showed relative normalization. The experimental results suggest that the hypophyseal-adrenal system and renal function are closely coupled regulatory mechanisms for adaptive reactions of the cardiovascular system and for fluid-electrolyte metabolism during acute adaptation of the human body to reduced gravity.

Adaptation, Physiological↗

Comparison of physiological effects of head-down tilting and immersion on the human body.

Among the methods simulating weightlessness, effects on the human body, head-down tilting and water immersion are very useful. The purpose of the present investigation was to carry out a comparative study of water balance and water-protein composition of the blood using the above two methods to simulate the physiological effects typical of an acute stage of weightlessness adaptation. The results of the 7-d head-down tilting and immersion experiments allow the following conclusions: More pronounced changes in water balance and water-protein composition of the blood during immersion seem to indicate that immersion produces a greater effect on the human body; The pattern of changes during immersion and tilting suggests that the adaptation period to immersion takes a longer time; These findings give evidence that immersion, compared with head-down tilting, reproduces more closely effects of acute adaptation to simulated weightlessness.

Adaptation, Physiological↗