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Biomedical subjects

V E Zaĭchik

Publications and source records attributed to V E Zaĭchik.

7 recordsLinked to original sources

[Bone tumor macroelements].

Neutron-activation method was employed to determine the concentration of magnium, sodium, chlorine, phosphorus and calcium in different bone tumors. In relation to normal skeletal tissue in tumor tissues higher concentrations of chlorine and sodium but lower concentrations of calcium and phosphorus were found. The greatest changes in the macromolecular content were noted in sarcoma tissues. Bone tumors differ reliably one from the other by concentrations or ratios of macroelements concentrations, this fact may be used for the differential diagnosis.

Adolescent

[The functional state of the thyroid gland following partial pancreatectomy].

In Wistar rats a study was made of a functional condition of the thyroid gland 1, 6 and 24 hours after partial pancreatectomy. The following signs-served as criteria of a functional condition of the gland: the amount of neutrone-activated iodine in iron, iodine-absorptive capacity of the gland by I131, the amount of protein-bound stable and radioactive iodine in the blood, a morphological condition of the gland structures. It was demonstrated that, despite the initial intensification of the process of synthesis and secretion in the thyroid gland, its secretory activity fell by the end of the experiment. This reduction is regarded as an adaptive response to partial insulin deficiency.

Animals

[The chemical element content of mixed unstimulated saliva from a healthy subject].

The levels of 21 chemical elements (N, Na, Mg, P, Cl, K, Ca, Sc, Cr, Mn, Fe, Co, Cu, Zn, Se, Br, Rb, Sr, Ag, Sb, Hg) were measured in 52 normal subjects aged 18 to 35 years with the use of a complex of instrumental methods including the neutron activation and x-ray fluorescence analysis. Effects of day time, season, sex and age on salivary composition were examined. The measured concentrations of chemicals in mixed nonstimulated saliva were different in each individual; some of them were liable to change only in the course of 24 hrs, therefore the time for saliva collection had to be strictly defined: 10-12 a.m. were found the optimal hours for saliva collection. Neither sex, nor age, nor season influenced the concentrations of the examined 21 chemicals, except Hg whose concentration grows with age.

Adolescent

[Determination of nitrogen, fluorine and phosphorus in osseous tissues by photonuclear activation].

A method of instrumental photonuclear activational analysis is developed for estimation of nitrogen, fluorine and phosphorus in bone tissue samples. The irradiation with maximal energy 15.6 MeV, obtained on linear accelerator of electrons LUE-25 RIMR AMN USSR, was used for activation. Estimations were carried out by the relative method with recording the intensity of positron radiation of 13N, 18F and 30P in samples and standards by means of device for gamma-gamma-coincidence. In chosen regimens of the analysis the statistical errors of nitrogen and phosphorus estimation did not esceed 1.5%, of fluorine-5%; the sensitivity of the method for nitrogen was found to be 0.06% for fluorine-0.006%, for phosphorus-0.12%; on analysis of recovery the relative standard deviation in results accounted for nitrogen-5.4%, for fluorine-6.7% for phosphorus 6.2%. Correctness in concentrations of the elements, estimated by the method described, correlated with the data, obtained in activation with reactor neutrons and with 14MeV generator neutrons.

Activation Analysis