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Biomedical subjects

V Elenius

Publications and source records attributed to V Elenius.

18 recordsLinked to original sources

Field quadrant asymmetry in perimetric thresholds: results of normal and red-green-deficient persons.

Perimetric thresholds of normal and red-green-deficient persons were measured using three colored test stimuli and a low-intensity white background. Meridians of 45 degrees, 135 degrees, 225 degrees and 315 degrees were tested within 30 degrees peripherally. A statistically significant sensitivity difference between the quadrants was found at eccentricities of 5-30 degrees from the center with the highest sensitivity in the lower temporal field and the lowest one in the upper nasal field, this difference being slightly larger when tested with red (615 nm) or violet (443 nm) light compared with blue-green (497 nm) test light. No difference in the field quadrant sensitivity was observed between the results of the series of normal and red-green-deficient persons.

Adolescent↗

Perimetric testing of tritan deficiency.

Three members of a family with dominantly inherited juvenile optic atrophy tested with a computerized perimeter employing violet and blue-green test lights and low-intensity white background, all showed larger reduction in the relative sensitivity to violet light in the more central parts of the visual field compared with the periphery within 30 degrees from the center. Two subjects had typical optic atrophy, centrocecal scotoma and lower than normal visual acuity. In 1 subject with good visual acuity of both eyes, no optic atrophy was observed but there was impairment in the luminosity function (tested with white test object on white background) of the peripheral visual field.

Adult↗

Rod thresholds in dominantly inherited juvenile optic atrophy.

Three members of a family with dominantly inherited juvenile optic atrophy with tritan type of colour vision deficiency all showed dysfunction of the rod mechanism tested with green light after 30 min of dark adaptation. Two subjects had typical optic atrophy, centrocaecal scotoma and lower than normal visual acuity. In 1 subject with good visual acuity of both eyes, no optic atrophy was observed, but there were, in this case, reduced peripheral parts of the standard visual fields.

Adult↗

Visual thresholds measured with red test object on backgrounds of high and low luminance.

Visual thresholds measured at the central and midperipheral visual field have been tested in the eyes of a series of 10 healthy normal persons using a monochromatic red test light object (Goldmann area III, 25' of arc in the visual field) of 632 nm wavelength presented on white backgrounds of 150 cd/m2 (5000 K) and 1 cd/m2 (2800 K) luminance, as well as with no background illumination following a 45 min period of dark-adaptation. Another series of 10 normal subjects were tested with an equally large white (2800 K) test object shown on a white background of 1 cd/m2 (2800 K) luminance. Results obtained in congenital and acquired achromatopsia as well as in three relatively mild cases of rod-cone dystrophy have been related to the normal thresholds.

Adult↗

Photopic tangential perimetry.

A large absolute paracentral ring scotoma was found in both eyes of a 60-year-old woman with progressive cone dysfunction but with normal rod function using for the perimetry a white tangential screen of 200 cd/m2 luminance and a 632 nm laser test light. No visual field defect could be found in this patient using the Goldmann perimeter employing white test objects on the standard 10 cd/m2 white background. Further developments of a photopic tangential perimetry system are suggested.

Female↗

Rod saturation perimetry. Testing of the cone function with achromatic objects.

Restriction of the visual fields in bright illumination and return of the peripheral field in lower illumination were the main complaints of a 59-year-old woman with slowly progressive cone dysfunction and normal rod function. She had normal central visual acuity, normal central color vision, and normal visual fields when tested with the standard Goldmann perimeter. A large ring scotoma was demonstrated in both of her eyes, using tangential perimetry employing a white background of 85% reflection and test objects darker than the background. Using a background of 250 candelas/sq m, which caused a complete saturation of the rod function, the scotoma was absolute. Black test objects of 5% reflection were not seen.

Color Perception↗

Visual thresholds in the deutan type of red-green deficient colour vision.

Defective temporal integration for a foveally fixated 100' of arc red (660 nm) Btest flash presented on a 30 cd/m2 yellow ( Schott , OG 530) background was measured in subjects with deuteranopia , as well as in subjects with anomalous trichromacy of the deutan type. The mean integration time was 77 +/- 17 ms in 12 normal subjects but only 35 +/- 6, 46 +/- 11 Band 41 +/- 15 ms in respectively 6 subjects with deuteranopia , 7 with extreme deuteranomaly Band 9 with deuteranomaly . An increase in the test duration from 10 to 200 ms increased the mean relative sensitivity by 0.85 +/- 13 log units in the normal subjects compared with 0.45 +/- 0.05, 0.57 +/- 12 and 0.56 +/- 19 in subjects with deuteranopia , extreme deuteranomaly and deuteranomaly .

Adolescent↗