[Changes in the plasma levels of fibrinopeptide A in acute myocardial infarction after administration of intravenous streptokinase].
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Biomedical subjects
Publications and source records attributed to V Eliseo.
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A group of heart patients and another group of healthy subjects have been studied and their systolic intervals (PEP-LVET - PEP/LVET ratio and the telediastolic index) evaluated using the mechanocardiographic system. In both long-standing and recent heart patients, the parameters studied showed significant deviations from the norm. These were even more marked after exercise on the ergonometer bicycle. Acute doses of digitalis reduced deviations from the norm observed under basal conditions and after exercise. Polycardiography, it is concluded, assists in the gathering of extremely valuable information about cardiac performance in relation to latent cardiac insufficiency. Especially useful information can be deduced from PEP indications and from the PEP/LVET ratio. The use of digitalis is suggested for physically active post-infarction subjects in order to give greater tolerance of physical exercise. The concept of long-term polygraphic studies as part of out-patient follow-ups on such patients is outlined.
An assessment was made of the fourth heart sound as a non-invasive clinical and instrumental aid in the diagnosis of latent cardiac insufficiency. The sound was recorded in various decubitus positions in a series of healthy subjects and patients with recent and past infarction, under basal conditions, after exercise on the cycle ergometer, and after digitalis i.v. Persistence of the fourth sound in the standing position was noted in nearly all infarct patients, while its incidence decreased significantly after digitalis. It is felt that this finding can be interpreted as evidence of the non-existence of latent heart failure. Its further investigation and correlation with other invasive and non-invasive instrumental examinations is proposed.
Frank's technique has been used to study the behaviour of the vectorial loop in 20 subjects wearing fixed frequency pacemakers. A broad study has been carried out non characteristics and modalities of transmission of the artificial stimulus. The morphological features of the vectorcardiogram differ in accordance with the location of the stimulated point. Special attention is paid to the possibility of the catheter-electrode penetrating the coronary sinus during right intracavitary pacing and the consequent vectorial and radiological characteristics such an eventuality involves. Some remarks are offered on the orientation of the extrastimulus, depending on its point of origin. It is concluded that knowledge of the course of the vectorial curve may be extremely useful for establishing the site of the extrastimulus in pacemaker wearers.
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