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Biomedical subjects

V Escobar

Publications and source records attributed to V Escobar.

At least 19 recordsLinked to original sources
PubMed1999

Delayed repair of skin cancer defects.

PURPOSE: A review of surgical outcomes in 280 patients who underwent in-office excision of skin lesions, open wound therapy, and delayed reconstruction is presented. Advantages of open wound therapy and delayed reconstruction are discussed. PATIENTS AND METHODS: The surgical records of all patients treated between January 1, 1994 and December 31, 1996 were evaluated for outcome and complications. RESULTS: One hundred seventeen patients presented with biopsy-confirmed malignant skin lesions of the head and neck. After surgical excision of the malignancy, the wounds were treated with a semiocclusive dressing while waiting for the results of the biopsy report and reconstruction (open wound therapy). Eighty-nine percent of the residual skin defects were repaired within 10 days. The remaining 11% were closed within 35 days. Except for one allergic reaction to neomycin and slight blood oozing from the wound in two patients, no other complications occurred. CONCLUSIONS: Open wound therapy is an effective method for managing skin defects after excision of malignant lesions. It is cost-effective and can be done quickly as an in-office procedure under local anesthesia without complications.

Aged↗
PubMed1984

Oral gonococcal infection.

2 patients are described in whom the occurrence of central papillary atrophy of the tongue (CPA) was concurrent with gonococcal stomatitis. The significance of this finding is discussed in an attempt to highlight the fact that, in many patients, infectious processes may be responsible for the production of CPA. Previous reports combining gonococcal stomatitis and central papillary atrophy of the tongue were not found during a thorough review of the world literature.

Adult↗
PubMed1983

Clouston syndrome: an ultrastructural study.

A previously undescribed French-Canadian family affected with Clouston Syndrome (Hypohidrotic Ectodermal Dysplasia) is described. Ultrastructural study of the hair shows disorganization of the hair fibrils with loss of the cuticular cortex. The SEM findings are consistent with the model, suggesting a biochemical defect in the keratin of the integumentary system.

Child↗
PubMed1980

Familial facial asymmetry (autosomal dominant hemihypertrophy?).

A family in which several members were affected with facial hemihypertrophy is reported. Mandibular asymmetry and maxillary hypoplasia were common to all affected persons in this family. An autosomal dominant mode of inheritance appears to be the pattern of transmission of such a condition.

Adult↗
PubMed1979

The human X-chromosome and the levels of serum immunoglobulin M.

The serum concentrations of immunoglobulins G, A and M were measured in a sample of 93 pairs of monozygotic twins, their spouses, and their offspring. The hypothesis that the human X-chromosome carries genes which control the levels of immunoglobulin M was tested with three different approaches. Our results indicate that environmental factors are primarily responsible for the observed variation in the levels of IgG and IgA. The variance of IgM seems to be mostly the result of X-linked gene effects, with women having higher IgM levels than men.

Female↗
PubMed1979

Genetic structure of the Queckchi Indians. Dental microdifferentiation.

Nine oral morphologic characters were investigated. Their frequencies are compared with those published for other populations. The possibility of using such characters to estimate genetic distance between populations is discussed and the conclusion is reached that, although previous studies have suggested this to be a valid approach, further studies testing this subject are needed.

Adolescent↗
PubMed1979

Analysis of intrafamilial correlations, serum levels of IGM and the human X-chromosome.

The serum concentrations of immunoglobulin M (IgM) were measured in a sample of 93 monozygotic twin pairs, their spouses, and their offsprings. The hypothesis that the human X chromosome carries genes that control the levels of IgM was tested with two different approaches neither one of which provided conclusive evidence to support the IgM X-linked gene hypothesis.

Female↗
PubMed1978

Aarskog syndrome. New findings and genetic analysis.

A patient had several unusual findings that, to our knowledge, have not previously been reported in the Aarskog syndrome (facio-digital-genital syndrome). On the basis of published pedigrees, the data strongly support an X-linked recessive mode of inheritance.

Abnormalities, Multiple↗
PubMed1978

Femoral hypoplasia-unusual facies syndrome, from another viewpoint.

A female infant with the "femoral hypoplasia-unusual facies" syndrome is presented. Most of the findings observed in this child have also been described in the "caudal regression syndrome". The similarity and probable identity between these two syndromes is discussed on the basis of our patient and others from the literature.

Abnormalities, Multiple↗
PubMed1978

Multiple pterygium syndrome.

After treating a 12-year-old patient with multiple pterygium syndrome, we ascertained the minimal diagnostic criteria of pterygia in the neck, axilla, antecubital, and even popliteal areas; evidence supports autosomal recessive inheritance for this syndrome.

Adult↗
PubMed1978

Phenotypic and genetic analysis of the silver-Russell syndrome.

A family is reported in which two half-siblings present clinical findings suggestive of the Silver-Russell syndrome (SRS). The available published literature on SRS is reviewed and the variable expression of the syndrome demonstrated. A review of published pedigrees of the syndrome suggests that in a small percentage of cases, SRS has a genetic etiology.

Child, Preschool↗