[Hypertensive cardiomyopathy in the practice of primary therapist and cardiologist (lecture)].
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Biomedical subjects
Publications and source records attributed to V F Benevskaia.
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Nebivolol was given to 30 hypertensive postmenopausal women as monotherapy (5-10 mg/day) or in combination with hydrochlorothiazide. Clinical effect was achieved in 76.6 and 86.7% of women on mono- and combination therapy, respectively. Hypotensive effect was confirmed by 24-hour blood pressure monitoring. Blood pressure lowering was associated with decrease of total peripheral resistance and regression of left ventricular hypertrophy. Nebivolol appeared to be metabolically neutral and only sporadic adverse effects were registered.
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The cephalosporin antibiotic zinnat was given to 171 outpatients with bronchopulmonary infections. Pneumonia patients received 500 mg, patients with acute bronchitis or exacerbation of chronic bronchitis 250 mg twice a day. The recovery was registered in 97.7, 98.8 and 91.8% of patients, respectively. The drug proved effective, low-toxic, convenient in use. Wide-spectrum action, significant activity against both gram-positive and gram-negative pathogens make zinnat a promising drug for outpatient treatment of bronchopulmonary infections.
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