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Biomedical subjects

V F Kubyshkin

Publications and source records attributed to V F Kubyshkin.

49 records · Page 3Linked to original sources

[The pathogenetic aspects of diabetic involvement of the heart].

As many as 107 patients with diabetes mellitus were enrolled in the study. It has been found out that under diabetic metabolic disturbances there occur significant changes in structural-and-functional characteristics of proteins, including myocardial ones, believed to be of much importance to the pathogenesis of diabetic affection of the heart and to the functional state of the myocardium.

Adolescent↗

[The cytochemical characteristics of the blood polymorphonuclear leukocytes in dilated cardiomyopathy and an inflammatory myocardial lesion].

Using methods of cytochemical investigation of the blood polymorphonuclear leucocytes (PMNL), parameters have been studied, characterizing the systems of biological defence and bioenergetics in patients with dilated cardiomyopathy (DCMP), infectious allergic myocarditis (IAM) and myocarditic cardiosclerosis (MCS). DCMP patients showed depression of NBT--test against the background of the increase in the cationic proteins (CP) level in the blood PMNLs, which was a major cytochemical feature. G-6-PhDG activity was increased in IAM patients against the background of high values of NBT-test. Increased values for G-6-PhDG, CP, phosphatases in the presence of low levels of myeloperoxidase in the blood PMNL suggest chronic inflammatory process in the myocardium. Investigation into the cytochemical parameters of bioenergetic and biological defence of the blood PMNL in patients with DCMP, IAM and MCS permits optimization of the diagnosis and treatment policy in the aforementioned nosological entities.

Adolescent↗

[The characteristics of the psychological status of myocardial infarct patients and geomagnetic factors].

An analysis is presented of myocardial infarction (MI) incidence during a 366-day period. Results were compared with prognostic and real unfavourable days by geomagnetic values (data of the Geophysical Institute in Göttingen (Germany)). There was no essential morbidity rise in the unfavourable days but a greater number of IM was noted during coincidence of prognostic and real unfavourable days. Among the patients persons with a definite psychological background prevailed. It is suggested that a greater sensitivity to geomagnetic factors is acquired during psychological and physical readaptation reflecting destabilization of the regulatory systems of the human body.

Adult↗

[The bioenergetics system of the blood lymphocytes in infectious-allergic myocarditis].

46 patients with infectious-and-allergic myocarditis (IAM) and 46 patients with myocarditic cardiosclerosis (MCS) were studied for cytochemical parameters of blood lymphocyte bioenergetics. In IAM, cellular metabolism was found out to be disturbed, with the activity of G-6-PDG in spontaneous NST-test being risen against the background of depression of NAD- and NADP-diaphorases, lowering of the endogenous cytochrome "C" content and activity of alpha-GPDG. One third of IAM patients demonstrated protracted variant of the disease course by a study into the bioenergetic status of blood lymphocytes. Examination of parameters of blood lymphocytes energy exchange permits establishing more differential and diagnostic criteria for inflammatory lesion of the myocardium.

Adolescent↗