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Biomedical subjects

V F Minenko

Publications and source records attributed to V F Minenko.

8 recordsLinked to original sources
PubMed1997

Influence of measurement geometry on the estimate of 131(I) activity in the thyroid: Monte Carlo simulation of a detector and a phantom.

An approach for evaluating the influence of measurement geometry on estimates of 131(I) in the thyroid from measurements with survey meters was developed using Monte Carlo simulation of radiation transport in the human body and the radiation detector. The modified Monte Carlo code, EGS4, including a newly developed mathematical model of detector, thyroid gland, and neck, was used for the computations. The approach was tested by comparing calculated and measured differential and integral detector characteristics. This procedure was applied to estimate uncertainties in direct thyroid-measurement results due to geometrical errors.

Adolescent↗
PubMed1996

The feasibility of using 129I to reconstruct 131I deposition from the Chernobyl reactor accident.

Radioiodine released to the atmosphere from the accident at the Chernobyl nuclear power station in the spring of 1986 resulted in large-scale thyroid-gland exposure of populations in Ukraine, Belarus, and Russia. Because of the short half life of 131I (8.04 d), adequate data on the intensities and patterns of iodine deposition were not collected, especially in the regions where the incidence of childhood-thyroid cancer is now increasing. Results are presented from a feasibility study that show that accelerator-mass-spectrometry measurements of 129I (half life 16 x 106 y) in soil can be used to reconstruct 131I-deposition density and thus help in the thyroid-dosimetry effort that is now urgently needed to support epidemiologic studies of childhood-thyroid cancer in the affected regions.

Cesium Radioisotopes↗
PubMed1996

Radiation effects on the population of Belarus after the Chernobyl accident and the prediction of stochastic effects.

Evaluation of conditions of exposure during the post-accident period makes it possible to identify two periods in the radiation exposure of Belarus's population. As a result of our investigations we obtained data about doses for four different categories in the exposed population: people who lived in the contaminated territories without evacuation and relocation; evacuated people: cleanup workers ("liquidators"); and people who were exposed in childhood, especially for thyroid exposure. The total doses for these categories in different time periods were analysed. Evaluation of doses received by the Belarusian population due to the Chernobyl accident shows no evidence of doses, that could lead to the deterministic consequences of radiation exposure. For all exposed groups we made predictions about different types of stochastic consequences of exposure.

Abnormalities, Radiation-Induced↗
PubMed1983

[Computerized program for calculating the dose distribution generated by intracavitary linear sources of gamma radiation].

One can achieve a high precision in the dosing of a session of intracavitary radiotherapy by rapid computerization of the treatment time that is necessary for obtaining a certain dose in a pathological focus taking account of an actual location of radiation sources in the process of irradiation. The authors have developed an algorithm and drawn up a program for computer ES-1022 to calculate a dose rate in any point of an irradiated volume from the system of gamma-radiation sources oriented arbitrarily in space. As part of a hard- and soft ware dosimetric complex, the above program provides for the calculation of the treatment time by a set dose; the time is necessary for supplying this dose to a tumor focus taking account of an actual location of radiation sources during a session of irradiation. The whole computer procedure from the moment of obtaining necessary anatomo-topographic information in the form of two x-ray pictures up to the output of an irradiation session time value and other information into the alpha-numeric printer takes 3-5 min. The program makes it possible to calculate dose distribution in any preset plane (up to 4 planes at a time) of an irradiated volume.

Brachytherapy↗
PubMed1983

[Soft- and hardware support for the setup for computer tracking of radiation teletherapy].

A hard and soft ware computer assisted complex has been worked out for gamma-beam therapy. The complex included all radiotherapeutic units, including a Siemens program controlled betatron with an energy of 42 MEV computer ES-1022, a Medigraf system of the processing of graphic information, a Mars-256 system for control over the homogeneity of distribution of dose rate on the field of irradiation and a package of mathematical programs to select a plan of irradiation of various tumor sites. The prospects of the utilization of such complexes in the dosimetric support of radiation therapy are discussed.

Computers↗
PubMed1983

[Evaluation of radiation treatment effectiveness using the rated standard dose (RSD) under different irradiation conditions].

In the evaluation of efficacy or while comparing various irradiation schemes with the help of the RSD concept one should consider the effect of various conditions of patient's irradiation (energy, a field size, dose rate, etc.) on the biological efficacy of absorbed energy. The radiobiological effect of various irradiation schemes should be evaluated by a common scale, therefore factors altering dose biological efficacy should be considered within the limits of the same RSD formula. In our opinion, there is no sense in individualizing the evaluation of an effect of the dose rate on the biological efficacy of radiotherapy as a separate RSD formula. The incorporation in the RSD formula of an empirical expression of RBE dependence on the dose rate within the range of 0.13-300 Gy/hr. and factors of the dependence of dose biological efficacy on its spatial distribution (energy, a field size) gives an opportunity not only to consider more correctly changes in patient's irradiation from session to session but also makes it possible to apply it to fractionated and protracted irradiation schemes.

Evaluation Studies as Topic↗