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Biomedical subjects

V F Nadalini

Publications and source records attributed to V F Nadalini.

At least 19 recordsLinked to original sources

Receptors mediating contraction of isolated human vas deferens.

A large body of evidences has suggested the role of adrenergic, opioidergic and other peptidergic receptors in the mediation of animal vas deferens motility. Different animal species showed different neurochemical patterns, so it is to be expected that human vas deferens has its own specific response to several substances, in relation to its peculiar function. In this study we report on the effects of monoaminergic (norepinephrine, dopamine, serotonin, isoproterenol, cholinomimetic drugs) and opioidergic (morphine, buprenorphin, beta-endorphin, met-enkephalin and dynorphin) agonists on isolated human vas deferens motility. Norepinephrine and dopamine provoked complex patterns of motility while opioids did not affect the field electroinduced contractions. The implications of this finding are discussed in relation to human vas deferens function.

Aged↗

[Liquid embolization of the renal artery with absolute ethanol].

Absolute ethanol is a new agent for use in embolization which has demonstrated excellent efficacy, is simple to manage, and above all is innocuous in case of reflux into the aorta. A part from provoking irreversible occlusion of the complete renal artery circle, embolization with ethanol provokes direct cellular toxic necrosis comparable with a true mummification. This is of fundamental importance during palliative embolization for renal cancer or in all cases of medical nephrectomy for non-neoplastic disease. Results of the use of liquid embolization of the renal artery with absolute ethanol are presented, the technique, described, and mechanisms of action analyzed based on histologic findings.

Embolization, Therapeutic↗

Fluoroscopically guided skinny-needle aspirative biopsy in normal and suspected lymph nodes in urologic cancer.

The authors present their experience with transperitoneal thin-needle biopsy of the retroperitoneal lymph nodes. This method is a means of improving lymphographic diagnosis in suspected lymph node metastases, the small contrast defects serving as a sign. The high rate of false-negative results makes its use unadvisable in patients with negative lymphography where the sample cannot be aimed at but is multiple and randomized.

Biopsy, Needle↗

[Percutaneous dilatation of renal artery stenoses. Apropos of 7 cases].

The authors report the results of percutaneous dilatation of renal artery stenoses, performed on 8 occasions in 7 patients. One patient had bilateral stenoses which were operated at two separate occasions. The authors had no complications and they confirm the stability of the results with a follow-up of up to 2 years. In the 4 cases with an isolated unilateral renal artery stenosis, dilatation of the artery led to normalization of the blood pressure within hours of the operation. When there was another cause for hypertension apart from the renal artery stenosis, the dilatation did not cause the blood pressure to return to normal, although the anatomical result was confirmed on arteriography. The authors then review the literature and compare the complications of surgery for renal artery stenoses with those occurring during or after percutaneous dilatation of the renal artery lumen. Because of the quality of the results, the complication rate and the good results obtained with percutaneous dilatation in the literature, the authors conclude that percutaneous dilatation of the renal artery lumen is the treatment of choice for these stenoses. The indication for this operation can be extended, as its aim is not only reduction of hypertension, but also to improve renal function and to avoid the risk of thrombosis on a very narrow stenosis. In this way, the indications for this operation extend to include a population which, up until now, has been excluded from surgery, such as elderly patients, patients with coronary disease, or with renal failure.

Aged↗

[Embolization of the inferior mesenteric artery in hemorrhagic bladder neoplasms after failure of hypogastric arteries embolization].

The authors report 3 cases of revascularisation through the inferior mesenteric artery of bladder tumors which had previously been treated by transcatheter occlusion of both hypogastric arteries because hemorrhage. New uncomplicated embolizations of the inferior mesenteric artery are performed in 2 cases and recurrency of the bleeding was stopped.

Acrylic Resins↗

[Histological follow-up after implantation of grains of I-125 for prostatic cancer].

The authors report a preliminary study of 12 cases of carcinoma of the prostate confined to the prostate (T1, T2, T3, NO, MO) treated by pelvic lymphadenectomy and the implantation of grains of I 125 in the prostatic tissue. Irradiation continued for six months, providing most dose of 100 Gy in the prostate. Interstitial irradiation caused not only the destruction of tumour cells but also "radiation prostate" lesions with vascular obliteration which itself caused sufficient impairment of the vitality of the prostatic tissue for any residual tumour to disappear with a frequency which increased with the time elapsing between the follow up prostatic biopsy and the implantation of radioactive iodine. Experience remains limited but the initial figures given here suggest the validity of continuing along these lines.

Adenocarcinoma↗

[Percutaneous embolization of renal cancer. Clinical evaluation (author's transl)].

The authors deal with 17 cases of renal adenocarcinoma treated with preventive embolization, widened nephrectomy and total parenteral nutrition, as well as one case of palliative definitive embolization in a patient who could not be operated. The most remarkable clinical aspects turned out to be in the easier and safer maneuverability under surgery, a decrease in mortality during and after the operation, reduced consumption of blood units, and a better which were treated only with purely surgical therapy.

Adenocarcinoma↗

Hematuria due to circumaortic left renal vein.

A patient with benign recurrent hematuria underwent selective renal venography, manometric registration of pressure levels in the renal veins, and renal biopsy which indicated the circumaortic left renal veins was responsible for intermittent hematuria and proteinuria.

Adult↗

[Therapeutic angiographic occlusion with a modified autologous clot. Case report].

Therapeutic arterial embolization with autologous clot is readily applied in urology. The procedure is particularly effective in those cases where a temporary blockage of the artery is required, enough to cause a definitive haemostasis in noble parenchymas sensitive to ischaemia. However this method is not limited only to poor risk patients ("life-threatening"); it may be preferable to surgical operation, as in the case studied, of postraumatic, intraparenchymal arterovenous fistula. In their presentation, the authors also take into consideration several technical side-effects, helping towards correct execution.

Abdominal Injuries↗

[The subclavian approach as an alternative to the femoral approach in selective cervicocephalic phlebography (author's transl)].

The authors describe the technique employed for selective catheterization of the main mediastinal trunks and the veins of the brachiocephalic and cervicocephalic regions by means of the subclavian approach. The importance and advantages of this procedure as an alternative to the femoral approach, especially if this is contra-indicated, are emphasized.

Catheterization↗

Multiple sampling for parathyroid hormone by subclavian approach.

Selective venous catheterization with parathyroid hormone assay is a valuable procedure in the diagnosis and treatment of parathyroid tumors. The multiple sampling via the femoral vein is sometimes frustratingly uncertain and time consuming. The technique herein described is simpler, quicker, and less hazardous. It is accomplished via the subclavian approach, a relatively easier anatomic way, and utilizes a short single-curve catheter that gives a high degree of torsion control.

Adenoma↗

[Endo-urological techniques. New applications in two cases].

Two new indications for the application of endo-urological techniques are reported. One case involved recanalization of stenosis at the ureterovesical junction, while in the other case a double J ureteral endoprosthesis was extracted by the transnephropyelostomy percutaneous route.

Adult↗