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Biomedical subjects

V F Rusiaev

Publications and source records attributed to V F Rusiaev.

At least 19 recordsLinked to original sources

[New methods and equipment for studying the hemostatic system (review of the literature)].

The author analyzes the principles and reviews the ranges of application of conductometric, filtration rapid method for studies of formed element aggregation in stabilized blood, hemostographic, photodynamic method for blood clotting registration, superfusion method for assessment of hemocoagulation tissue factor release reaction. He comes to a conclusion that the diagnosis may become objective, rapid, reliable, and accurate if biophysical characteristics of the hemostasis are investigated, their informative value assessed, and measuring equipment for hematologic laboratories designed and commercially produced.

Blood Coagulation Tests↗

[Dynamics of peripheral nerve procoagulant and fibrinolytic activity upon electrical stimulation].

The amount of procoagulative and fibrinolytic agents in cellular organoids was studied in the cat n. ischiadicus. All cellular fractions revealed high thromboplastic activity. Plasminogen, its activator, and proactivator were discovered in the ischiadic nerve. In dogs, the changes of functional state of nerves were accompanied by discharging of tissue thromboplastin and stimulators of fibrinolysis into the external medium with stimulaneous changes of intracellular contents of hemocoagulating factors. Thus, electric stimulation of the nerve intensified its thromboplastic activity, increased concentration of analogs of the plasma factors (II, VII, IX) and stimulation of fibrinolytic agents. The data obtained suggest presence of close enough interaction between the changes of functional condition of cells and dynamics of their procoagulative and fibrinolytic power.

Animals↗

[Factors of coagulation and fibrinolysis in somatic and autonomic nerve fibers and their role in the process of excitation].

Somatic and vegetative nerve fibres contatin a very active thromboplastin, antiheparin factor, proactivator, activator, plasminogen and plasmin. Fibrinolytic agents are more numerous in the nuerolemma than in nerve fibres. Plasmin and its activator are firmly bound with the tissue structure, unlike plasminogen and proactivator. It is supposed that these factors may be significant in the structural modification of protoplasm at excitation of cell elements.

Animals↗

[Electrokinetic properties of formed elements in blood exposed to physical factors].

Constant magnetic field (300 Oe), sound oscillations (40 Db 50-20000 Hz) and electromagnetic field (3 V/cm, 50--20000 Hz) decrease the electrophoretic mobility of erythrocytes and trombocytes of dogs and human blood red cells in in vitro experiments. Bitemporal effect of alternating electric current (0,05--0,2 mA/cm2) in the same frequency region is accompanied with a similar fall of electrokinetic index of dog formic elements. The greatest effect is recorded in the range of 5000--1000 Hz both for sound oscillations and electromagnetic field. The significance of resonance effects in biological systems in the region of 1000 Hz frequency is discussed.

Animals↗

[Conductometric method of studying aggregations of the formed elements of the blood].

To study an aggregation of formed blood cells a setup is proposed in which use is made of the conductometric method of measuring the resistance of a fine-pore filter through which the blood passes. A specially devised sensor allows it also to study the process of the cells aggregation in the vascular system of test animals and to control the dispersion of formed cells in the apparatus of extracoporeal circulation. Among advantages offered by the method are the objective character of measurement, the possibility of investigating the whole blood and due consideration of the part played by hydrodynamic factors.

Animals↗