The effect of penicillamine on serum digoxin levels.
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Biomedical subjects
Publications and source records attributed to V Fatourechi.
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Frequency of berign nodules in each lobes of the thyroid gland was determined in 214 consecutive patients who underwent thyroid operation. All cases had thyroid scintiscans. The right lobe was involved two times more than the left. In order to determine if this higher frequency was related to the naturally-occurring greater mass of the right lobe, fifteen normal thyroid glands from consecutive autopsy cases were bisected into halves and the weight of the two segments were compared. Although in 13 glands the right lobe was the larger one, the average weight difference was only seven percent.
Plasma concentrations of various parameters were determined before, during and for 24 hours after cardiopulmonary bypass surgery in 12 patients. Digoxin levels decreased uniformly during perfusion in all cases. Plasma magnesium levels decreased significantly during pump and remained low for 24 hours. Potassium and calcium levels were kept in the high normal range as a result of exogenous administration of these ions. Small amounts of magnesium added to the circuit in 7 patients did not change the pattern of hypomagnesemia. More vigorous magnesium replacement during bypass surgery may be required if hypomagnesemia is to be avoided.