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V Feiler-Ofry

Publications and source records attributed to V Feiler-Ofry.

At least 19 recordsLinked to original sources
PubMed1991

Does pupillary sparing oculomotor nerve palsy really spare the pupil?

We examined the pupillary cycle time (PCT) in eight elderly patients with isolated oculomotor nerve palsy (ONP) that was characterized by complete involvement of the extraocular muscles. In addition to advanced age, all patients had at least one other vasculopathic risk factor. Although in all cases the pupil was completely spared by clinical impression, the PCT was significantly prolonged compared with the other eye and well outside the normal range (mean 1590 +/- 212 msec on the involved side and 1076 +/- 110 on the uninvolved side). On re-examination, after an interval of 2-3 months, the PCT was either normal or markedly improved in all patients, paralleling the recovery of extraocular muscle function. These findings suggest that even in pure, noncompressive ONPs there is subclinical pupillary involvement. Repeated PCT examinations may provide an objective means to estimate recovery. Moreover, in the problematic subgroup of "pupil sparing" incomplete ONP, PCT monitoring during the first days may indicate possible progression of a compressive lesion.

Aged↗
PubMed1986

The pupil cycle time in Horner's syndrome.

Edge-light pupil cycle time has been introduced recently as a simple method for examining parasympathetic pupillary innervation. Since the sympathetic system is not thought to be involved in the light reflex, it was assumed that edge-light pupil cycle time would be unimpaired in lesions of the sympathetic pathways. In 12 patients with unilateral Horner's syndrome of different etiologies, the edge-light pupil cycle time was determined in both eyes. In all cases the edge-light pupil cycle time was significantly prolonged on the abnormal side. Patients with central, preganglionic, or postganglionic lesions showed the differences consistently. These data support the notion that the sympathetic system plays a role in the pupillo-dilating phase of edge-light pupil cycle time, presumably by exerting a tonic mydriatic effect. Since this tonic effect is lost in Horner's syndrome, leading to slowed redilatation, the edge-light pupil cycle time becomes prolonged. Thus, edge-light pupil cycle time may prove to be a valuable diagnostic test for Horner's syndrome.

Aged↗
PubMed1983

Clinical variability in vitreoretinal degeneration.

Three families with a wide range of vitreoretinal degeneration, median cleft face syndrome and skeletal anomalies are described. Their autosomal dominant transmission and phenotypic spectrum are presented. In view of the similarity between these patients and the clinical overlap existing between them, it is assumed that they are all the same entity forming parts of a continuum. As the pleiotropic gene has such different and varying expressivity with regard to the organ system involved, it is presumed that the dominance in this complex disorder is irregular.

Adolescent↗
PubMed1980

Retinal detachment in median cleft-face syndrome.

A 7-year-old boy had an unusual association of median cleft-face syndrome, a characteristic physiognomy, unilateral retinal dysplasia, and bilateral retinal detachment. Despite surgical treatment to both eyes he became blind. The hereditary pattern operating in this complex disorder was found to be consistent with an autosomal dominant trait.

Child↗
PubMed1980

Amiodarone keratopathy.

6 cardiac patients were found to present various degrees of corneal involvement following systemic treatment with amiodarone. The clinical pattern of the keratopathy, its benign course and the pathophysiology are discussed. Lacrimal insufficiency or incomplete blinking seem to contribute to the severity of the keratopathy.

Adolescent↗
PubMed1979

Lipoid proteinosis (Urbach-Wiethe syndrome).

A Jewish-Iranian family suffered from lipoid proteinosis. The 8 affected siblings were from consanguineous matings and presented a wide range of phenotypic expressions. Minimal manifestations in 2 heterozygote carriers and the possibility of autosomal recessive inheritance are discussed.

Adolescent↗
PubMed1977

Retinal breaks secondary to vascular accidents.

Seven retinal breaks occuring after occlusion of a major retinal arterial or venous branch were found in the eyes of six patients. Five holes were in the midretina, in a nonperfused avascular area corresponding to the sector affected by the vascular accident. One was a macular hole, and one a horseshoe tear outside the area involved in the vascular occlusion caused by traction of vitreous on a tuft of neovascular tissue. Five of the holes may have been caused by a kind of sequestration of the retina secondary to vascular insufficiency.

Adult↗
PubMed1973

[Homocystinuria].

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Consanguinity↗