PubMed Health⌕ Search

Biomedical subjects

V Fritzsche

Publications and source records attributed to V Fritzsche.

At least 19 recordsLinked to original sources
PubMed1993

[Management of depressed patients by family physicians. Questionnaire study in Hamburg].

METHOD: With the aid of a questionnaire specially developed for the purpose, general practitioners were questioned about their management of depressed patients attending their offices. A number of physician-related aspects that might have been the cause of the differences in prevalence and management of the patients, were investigated. RESULTS: Estimations on the part of the physicians that patients with psychological problems accounted for some 20% of their total case load were in agreement with figures obtained from other studies. Those specifically with depression accounted for 8.6%. The practitioners' assessment of their own competence in caring for depressed patients, and their cooperation with other institutions play a key role in the incidence of the diagnosis and the nature of medical treatment--by means of drugs, psychotherapy, referral, yes or no. The results obtained suggest a need to improve the psychiatric training of general practitioners and for closer cooperation with neurologists, psychologists, and hospitals.

Adult↗
PubMed1990

Cholesterol screening in 5,719 self-referred elderly subjects.

To assess the frequency of hypercholesterolemia as a potential major public health problem in the elderly, we studied 5,719 self-referred subjects greater than age 60 and 11,890 less than or equal to 60 years, whose nonfasting capillary blood cholesterol levels were measured during an 18-month screening in Cincinnati area grocery stores. We followed National Cholesterol Education Program guidelines for serum cholesterol (less than 200 mg/dl "desirable," 200-239 "borderline-high," and greater than or equal to 240 mg/dl "high"). Of 4,011 61-70 year-olds, only 19% had capillary blood total cholesterol less than 200, 38% were 200-239, and 43% greater than or equal to 240 mg/dl. Of 1,493 aged 71-80 years, only 20% had total cholesterol less than 200, 36% had levels 200-239, and 44% were greater than or equal to 240 mg/dl. In 215 subjects, 81 and over, 29% had total cholesterol less than 200, 36% were 200-239, and 35% were greater than or equal to 240 mg/dl. Application of the non-age, non-race, non-sex specific National Cholesterol Education Program guidelines to the elderly may necessitate followup and perhaps therapy in 71-81% of subjects, suggesting that the appropriate intervention approach be general population-oriented, rather than the individual detection, diagnosis, and treatment approach which presents a huge, expensive load for a relatively unprepared health care community.

Adult↗
PubMed1989

[Autopsy results in surgical-radiotherapeutic treatment of bladder carcinoma--conclusions for optimal radiologic therapy].

With 282 autopsied patients with bladder carcinoma, that were treated by combined operation and radiotherapy, conclusions are given for tendency in tumor spreading as well as for complications and late-effects of radiotherapy. In 24.5% of the cases tumor tissue was found within the bladder and in 30.5% of the cases within the minor pelvis. Metastases were found in 24.1% in iliac lymph-nodes, in 21.3% of the autopsy cases in abdominal lymph-nodes. Liver, lungs, bones, and kidneys are main organs for hematological metastasizing. Little or undifferentiated carcinomas and squamous cell carcinomas show a greater tendency to metastasize than highly and medium-differentiated ureteral carcinomas. The least radiotherapeutical complications and late-effects were found in a fractionation with daily 1.5 Gy and a total dose of 60 Gy (necrotising urocystitis 17.9%, proctitis 3.6%).

Carcinoma↗
PubMed1986

[Histologic changes in the normal bladder wall following fractionated irradiation--an animal experimental study].

The histopathologic alterations of the bladder wall were investigated in 180 rabbits irradiated with different fractionations and total focal doses. Animals sacrificed on week after the end of irradiation showed alterations of the urothelium (desquamation, increased polymorphism of nuclei vacuolizations) as well as oedematous and hyperemic reactions in submucosa and muscularis. These alterations became stronger when the single and total focal dose and the ret value were increased. Animals sacrificed three to six months after the end of irradiation showed dystrophic-sclerotic processes as well as vascular obliterations in the submucosa and muscularis. The alterations were only clearly visible in case of a total focal dose of at least 30 Gy. With regard to a minimization of histopathologic alterations of the bladder wall, a fractionation of 1.5 Gy per day has to be considered as favorable in radiotherapy of the carcinoma of the urinary bladder.

Animals↗
PubMed1985

[Asystolic pauses in atrial fibrillation. Incidence, dependence on the underlying disease and significance for pacemaker therapy].

The frequency and duration of asystolic pauses in atrial fibrillation was investigated in 100 consecutive patients using 24-hour ECG's obtained by Holter monitoring. Patients were subdivided, according to the length of the maximal RR-interval, into group A (no asystolic pauses over 2 seconds duration), group B (pauses between 2 and 4 seconds) and group C (asystoles over 4 seconds duration). Pauses longer than 2 seconds occurred in 57% of patients, but longer than 4 seconds only in 6 cases. A statistically higher frequency was seen in patients with permanent (78.3%) than in those with paroxysmal (24.5%) atrial fibrillation, and in patients with rheumatic valve disease (82.4%) in comparison with the rest (54.3%). In contrast, pauses over 2 seconds occurred in only 22.2% of general medical ward patients. Up to 50% of all asystoles in groups A and B were registered during the night, whereas a day-night variation for group C was not apparent. No correlation could be demonstrated between dizziness and bradycardic conduction in group A and B, but all patients in group C made such complaints during the monitoring period. Asystoles of up to 4 seconds duration in atrial fibrillation can be regarded as "normal"; longer asystoles must be anticipated particularly in patients with rheumatic valvular disease. It is only here that permanent pacemaker therapy appears to be indicated.

Adult↗