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Biomedical subjects

V G Borodulin

Publications and source records attributed to V G Borodulin.

At least 19 recordsLinked to original sources
PubMed2006

Pathomorphological peculiarities of damage to hair cells of the organ of corti in experimental sensorineural hearing loss.

Pathomorphology of the organ of Corti was studied on models of acute and chronic sensorineural damage to the acoustic analyzer. Peculiarities of hair cell degeneration, necrosis, and apoptosis in the organ were studied by light and scanning electron microscopy. The type of pathomorphological substrate in abnormalities of the organ of Corti depends on the intensity of the destructive exposure, but not on the nature of otopathological factors.

Animals↗
PubMed1995

[Diagnosis of osteomyelitis using Ga-67 citrate].

To increase the specificity of radionuclide diagnosis of purulent bone affections the authors used Ga-67 citrate which is incorporated into the circulating leukocytes. From the results of examination of 32 patients a comparative characteristics of the diagnostic value of osteotropic agents labeled with Tc-99m and Ga-67 citrate are given. The expediency of using Ga-67 citrate for indicating an inflammatory process in the phase of abscess formation is shown.

Adolescent↗
PubMed1991

[The ultrasonic diagnosis of changes in the hepatobiliary system in the practice of mass medical examinations].

Investigation of 1258 servicemen during the first year of their service using ultrasound scanning of the hepatobiliary system has shown signs of chronic cholecystitis in 170, chronic hepatitis in 70, pyelonephritis and renal calculi in 120; 25 servicemen were recommended for further medical examination. It has been concluded that ultrasound scanning must become part of obligatory investigations of conscripts.

Adolescent↗
PubMed1990

[Complex radiodiagnosis of osteomyelitis].

In 23 patients with chronic osteomyelitis roentgenography of the bones and three-phase scintigraphy including radionuclide angiography, investigation of the soft tissues and bones were performed. In comparison of the data of clinical examination, roentgenography and radionuclide methods of diagnosis, the correspondence of the data of radionuclide angiography to the phase of an inflammatory process was established.

Adolescent↗
PubMed1989

[Osteoscintigraphy in the diagnosis of psoriatic arthritis].

The authors presented the results of clinical, x-ray and osteoscintigraphic investigations of 133 psoriatic arthritis patients and 72 patients with common psoriasis. Osteoscintigraphy was performed using a routine method with 99mTc-pyrophos (USSR) and 99mTc-phosphone (Hungary) on gamma-camera LFOV (Nuclear-Chicago, USA). X-ray signs of the involvement of the osteoarticular system were noted in 69 (51%) patients with psoriatic arthritis and in 16 (22%) patients with common psoriasis. The method permitted the detection of the foci of RP hyperfixation in 129 (97%) patients with psoriatic arthritis and in 51 (70.8%) patients with common psoriasis. They were observed mostly in large and small limb joints, less frequently--in the vertebral column, cranial bones, thorax, and ribs. Thus, osteoscintigraphy is a highly sensitive method for the detection of active inflammatory foci of the osteoarticular system in psoriasis at all stages of arthritis development. It makes it possible to detect the spreading of arthritis and its preclinical forms.

Arthritis↗
PubMed1989

[Osteoscintigraphy in the diagnosis of latent psoriatic arthritis].

The authors analyze the findings of clinical, x-ray, and osteoscintigraphic examinations of 69 patients with psoriasis. Osteoscintigraphy has revealed latent psoriatic arthropathy in 49 (71%) patients. This method is an effective diagnostic tool for the detection of early involvement of the bone-and-joint system in psoriasis.

Adult↗
PubMed1988

[Functional state of the hypophyseo-adrenal system in patients with chronic alcoholism and various degrees of liver damage].

Chronic alcohol poisoning causes functional discoordination of the pituitary-adrenal complex expressed in suppression of the steroidogenesis of the adrenal cortex and in pituitary hyperproduction of ACTH. There is an interrelationship between the functional activity of the adrenal cortex and the severity of alcoholic involvement of the liver and between the intactness of pituitary function and the liver status. Antialcoholic treatment in conditions of complete alcohol abstinence leads to the normalization of ACTH levels in the peripheral blood whereas the steroidogenesis fails to be fully recovered.

Adrenocorticotropic Hormone↗
PubMed1986

[Hypophyseal-thyroid system in chronic alcoholism].

The levels of the thyroid hormones in the peripheral blood of patients with Stage I and II chronic alcoholism increased moderately at the expense of ejection activation in the blood but not hyperproduction of the thyroid and correlated with a decrease in the secretion of corticosteroids and an increase in the ACTH level. Disproportion of the T3 and T4 levels was in direct relation to a degree of alcoholic liver affection. In a long-term period following antialcoholic treatment hormonal function of the hypophyseothyroid system got back to normal.

Adult↗
PubMedDate not supplied

[X-ray and radiological aspects of primary and reconstructive jejunal interposition].

The late outcomes of primary and reconstructive jejunogastroplasty for motor and evacuatory dysfunctions of the graft and the gastrointestinal tract as whole were studied. Based of X-ray and radioisotopic findings, the paper shows the procedure used to form an artificial stomach from the large intestinal loop to obtain an invaginational valve at the site of jejunoduodenal atastomosis to be beneficial. This procedure makes it possible to recover the evacuatory function of the stomach removed, to prevent a number of postgastrectomic and postresectional disorders in the late postoperative period. Dynamic hepatobiliary scintigraphy was shown to be effective in examining the functional outcomes of gastric surgery and in diagnosing suspected reflux.

Digestive System Diseases↗
PubMedDate not supplied

[The function of the hypophyseal-thyroid system in chronic opisthorchiasis and its combination with the Salmonella typhi carrier state].

The hormonal function of the hypophysis and thyroid (TTG, T3, T4) and its dependence on hepatobiliary function, examined by hepatobiliscintigraphy, were studied by radioimmunoassay in 71 patients with chronic opisthorchiasis and in 18 chronic carriers of Salmonella typhi. in both groups. The decrease of T3 and T4 in the presence of normal TTG level was found. The imbalance of thyroid hormones activity is likely to be associated with hepatobiliary dysfunction. In chronic opisthorchiasis the hormonal disturbance may be one of the factors favouring the S. typhi carriership.

Adolescent↗
PubMedDate not supplied

[The hypophyseo-thyroid system in psoriatic arthritis combined with chronic opisthorchiasis].

Paper presents the data on the content of hypophysial-thyroid and hypophysial-adrenal systems' hormones obtained by means of radioimmune assay, and the data of timecourse hepatoscintibiligraphy with Tc 99 m TCK-15 of 94 patients (first group--48 patients with psoriatic arthiritis combined with chronic opisthorchiasis; second group--46 pure psoriatic arthritis patients). Statistically significant increase in the content of triiodinethyronine, thyroxine, hypophysial thyreotropic hormone, corticotropic hormone and significant reduction of cortizol and aldosteron contents were observed in case of mixed pathology. Thyroid hormones' level was directly connected with hepatic and gallbladder disfunctions. The above-mentioned changes belong to pathogenetic mixed-pathology factors which should be taken into account in elaboration of best treatment methods.

Adult↗