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Biomedical subjects

V G Kazimirov

Publications and source records attributed to V G Kazimirov.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[Use of plasmapheresis in intensive therapy of acute steroid-resistant rejection reaction in renal transplants].

For many years the treatment of steroid-resistant rejection (SSR) remains a common problem od renal transplantation. We used plasmapheresis (PPH) in the treatment of SRR in 29 renal transplant recipients. All patients had progressive deterioration of renal function and compatible biopsy histology. The first group (15 patients) was administered PPH with methylprednisolone (MP). The second group (14 patients) was treated by intravenous MP. There was no significant difference in the time of beginning and severity of rejection. In the PPH group the results were better: a significant increase in SSR reversion was attained (73.3%) in comparison with the control (42.8%), the number of grafts lost during the first year was less (26.7 versus 57.2%). Better results were observed in patients with high levels of serum anti-HLA antibodies. Their transplants functioned well during 12 months after SSR. Hence, PPH can be used in patients with SSR with high levels of anti-HLA antibodies.

Acute Disease↗
PubMedDate not supplied

[Peritoneal dialysis in the treatment of chronic renal failure].

Fifty-four patients were treated with peritoneal dialysis for terminal chronic renal failure. Clinical-laboratory indices were assessed in patients on chronic peritoneal dialysis. Advantages of continuous ambulatory peritoneal dialysis over hemodialysis are analysed in terms of social rehabilitation of the patients. Complications of chronic peritoneal dialysis as a method and algorithms of their treatment are outlined. The role of peritoneal dialysis as a preparatory stage before transplantation of the kidney is assessed.

Adolescent↗
PubMedDate not supplied

[Vesicoureteral reflux in renal transplantation].

Frequency of vesicoureteral reflux (VUR) variants was studied with miction cystography in 40 patients with chronic renal insufficiency. In 8 (20%) patients VUR was in their kidneys. The kidney was transplanted in 30 patients. The rate of urological complications was compared in ureterocystostomy by our technique and other procedures. In patients operated by our technique VUR did not occur. In 3 of 10 patients operated by other methods VUR into the transplant was found. Own kidney on the side of the reflux was removed in 4 patients after kidney transplantation. Indication for removal of own kidneys after allotransplantation of the kidney is urinary infection, arterial hypertension, pain in the lumbar spine. The proposed technique of ureterocystostomy has advantages in prevention of VUR into the renal transplant.

Adolescent↗