Biomedical subjects

V G Sutija

Publications and source records attributed to V G Sutija.

9 recordsLinked to original sources

PubMed2000

Effect of maternal weight gain on infant birth weight.

OBJECTIVE: To ascertain whether increased weight gain during pregnancy resulted in higher birth weight infants. METHODS: A database was constructed from valid data of a sample of 159 healthy women between 19 to 37 years of age. The inclusion criteria were: maternal age of 19-37 years, term gestations (37-42 weeks), a baseline weight obtained at 0-15 weeks gestation, and a final weight obtained within 2 weeks of delivery. Weight gain was calculated by subtracting baseline weight from the final weight. A documented height enabled calculation of BMI. A negative screen for gestational diabetes was required. RESULTS: Women with lower first trimester BMI (< 25) had infants of lower birth weight than women of higher BMI (> 25). Women with lower gain (< 35 lbs) delivered smaller infants than women with higher gain (> 35 lbs). Women of higher BMI and higher gain delivered the largest infants (F = 5.37; p = 0.0015). Underweight women (BMI < 19) gained less weight than women of normal weight (BMI 19-25), who gained the most weight. Obese women (BMI > 29) gained the least weight (F = 6.26; p = 0.0005). CONCLUSION: The results confirmed that excessive maternal weight gain in pregnancy (> 35 lbs), does result in higher birth weight infants.

Adult↗

PubMed2000

Neonatal echocardiograms of macrosomic neonates.

OBJECTIVE: To compare echocardiograms of macrosomic and healthy full term neonates whose weight was appropriate for gestational age (AGA). METHODS: Echocardiography was performed on 9 healthy full term AGA neonates and 15 macrosomic neonates. A data base was generated from valid echocardiographic measurements on each infant. RESULTS: Macrosomic infants were heavier than control infants and had a greater body surface area, but their mean cardiac dimensions were similar. The mean LVES volume was smaller than that of the control group when expressed as a fraction of individual LVED values (0.61 +/- 0.04 vs 0.64 +/- 0.02; p = 0.02). When comparing IVS/PW, it was observed that the ratio was up to and including 1.33 in the control group, while the upper limit of the ratio of the nondiabetic macrosomic infants was 1.6. The shortening fraction (SF%) was increased in comparison to infants of normal weight (40.67% +/- 3.34 vs 36.00% +/- 1.89; p = 0.0009). The thickened IVS did not elevate SF% by decreasing LVES; the macrosomic infants had a smaller LVES mean volume. CONCLUSION: IVS/PW ratio of macrosomic infants fell outside of the normal range. Macrosomic neonates were found to have an increased SF% secondary to a proportionally smaller LVES volume, regardless of IVS thickness.

Aorta↗

PubMed2000

Adolescent pregnancy: positive perinatal outcome at a community hospital.

OBJECTIVE: The objective of the present study was to determine the association between early maternal age and pregnancy outcome at a community hospital. METHODS: A retrospective cohort of 188 nulliparous patients was divided into three study groups of adolescent patients and a control group based on maternal age at the time of delivery. RESULTS: Younger adolescents had an excellent prenatal visit record. Overall complication rates were low and similar among groups. The cesarean section rates were not higher for younger adolescents in comparison to the control group. Duration of second stage of labor was shorter in adolescents than in the older patients (34.3 +/- 39.5 vs 59.5 +/- 39.9 min; t = 3.24; p = 0.002). There were no differences in mean gestational ages at delivery. The mean birth weights were lower in all adolescent groups compared to the control (ANOVA: F = 3.729; p = 0.0124). There were few NICU admissions in adolescent groups. CONCLUSION: Early maternal age (13 to 19 years) was associated with shorter duration of second stage labor and lower birth weight in a cohort of patients delivering at a community hospital.

Adolescent↗

PubMed1999

Ventricular dominance patterns in preterm infants.

OBJECTIVE: The purpose of the study was to determine EKG and 2-D echocardiographic criteria of ventricular dominance in preterm infants and select those by which ventricular dominance could be established by EKG alone. METHODS: A database was constructed from EKG and 2-D echocardiographic measurements on preterm infants ranging in gestational ages from 23 to 34 weeks and birth weights from 555-2490 g, and fullterm controls. Twelve-lead EKGs were obtained in the first 4 days of life in 12 preterm infants and in the first 24 hours of 4 controls. 2-D echocardiograms were performed with sweeps from the subcostal, parasternal, apical and suprasternal views and M-mode measurements in the short axis parasternal view on 11 of the preterm infants and 9 fullterm controls. RESULTS: A definite leftward QRS axis for the preterm infants (+90 degrees, preterm; +133.75 degrees, term; t = -5.63; p < 0.001) indicated a left ventricular (LV) dominance. But R/S in favor of LV dominance for preterm infants was apparent in V6 only. A pooled amplitude index for each ventricle based on R and S wave from V1, V2, V5, and V6 leads, showed LV dominance for the preterm infants with a trend toward RV dominance with increasing gestational age (F = 20.82; p < 0.001). RVD/LVED M-mode echo ratios confirmed the LV dominance in preterm infants. CONCLUSION: A healthy full term infant is born with RV dominance. LV dominance with a trend toward RV dominance with increasing gestational age was found in preterm infants by EKG and echo criteria.

Child↗

PubMed1990

Binocular advantage and visual processing in dyslexic and control children as measured by visual evoked potentials.

The role of visual processing in dyslexia continues to stir controversy. Previous research using early components of visual evoked potentials (VEP's) has revealed differences in visual processing between dyslexics and controls. VEP's have successfully indexed binocular advantage. Intrasensory functioning could conceivably be deficient in dyslexics. This study recorded VEP's in response to contrast-reversing checkerboards binocularly and monocularly from dyslexic and control children. The overall monocular and binocular amplitudes of the major positive peaks (P100) were greater for controls than dyslexics; however, contrary to the original hypothesis, the magnitude of binocular advantage was higher for dyslexics than for the control children. Stimulus factors had an effect, but did not interact with reading ability.

Analysis of Variance↗

PubMed1990

Age and binocular advantage: A VEP assessment.

Monocular and binocular visual evoked potentials (VEP's) were recorded in response to contrast-reversing checkerboard patterns of 2 check sizes (14 and 28 min arc) and 2 contrast-reversal rates (1.88 and 7.50 rps) in children (10 and 11-year-olds) and young adults (20 to 30-year-olds). The magnitude of binocular advantage, expressed as the ratio of the binocular to the average monocular response, was assessed by amplitude measurements of the major positive peak. The overall VEP amplitudes were larger for children than for adults across all conditions. The VEP amplitudes for binocularly viewed patterns were also consistently larger than the VEP amplitudes for the monocularly viewed patterns for both age groups. However, when the binocular advantage was expressed as a ratio of binocular to monocular average (MAV), the amplitude difference between the age groups was no longer apparent; although the children's average VEP responses were of a larger amplitude, the binocular advantage remained the same regardless of age.

Adult↗

PubMed1989

Nonlinearities in binocular visual evoked potentials in children.

Evidence is controversial in respect to the optimal conditions in which visual evoked potentials provide an objective measure of binocular visual function, related and unrelated to stereopsis, and there is little emphasis on the type of stimulus that produces facilitation in binocular recording. We investigated the effects of stimulus type (flicker or pattern), contrast, and temporal modulation on facilitation, which was defined as a binocular response greater than sum of monocular responses. Monocular and binocular responses to sinusoidally modulated flicker and grating patterns were recorded in children and Fourier analyzed. The relationship of the fundamental Fourier component for flicker and the second harmonic component for pattern were each examined as function of temporal modulation at two levels of contrast for monocular and binocular visual evoked potentials. Binocular facilitation was found across all conditions for flicker. Data suggest that processing of pattern and flicker has different sites of origin within the visual system. Facilitation in binocular visual evoked potentials also indicates that they are not a result of simple summation of monocular responses, since there appears a nonlinear component to such interaction.

Analysis of Variance↗

PubMed1979

Development of X- and Y-cells in kittens.

A contrast reversal stimulus was used to classify the retinal ganglion cells of kittens 3--12 weeks of age. At 3 and 4 weeks of age, the majority of the units were classified as Y-cells. The percentage of X-cells was similar to that of the adult at 5--6 weeks of age although other response properties were not adult-like. The angular size of the receptive field center was significantly larger than that of the adult through 5--6 weeks of age. An estimate of the position of the vertical meridian was obtained from the positions of the receptive fields in the visual field which permitted the calculation of the posterior nodal distance in kittens of various ages. From the posterior nodal distance, the linear extent of the receptive field center was determined. This showed that there is only a very slight increase in the linear size of the receptive field center from 3 weeks to adulthood.

Age Factors↗

PubMed1979

Classification of cat retinal ganglion cells into X- and Y-cells with a contrast reversal stimulus.

A contrast reversal (alternating phase) stimulus was used to study the responses of 150 retinal ganglion cells from 15 adult cats. Because the majority of the cells did not show perfect linear spatial summation, a ratio of the firing rates at two time periods was used to express the degree of nonlinearity. Y-cells showed a high degree of nonlinearity, and their mean null ratio was significantly lower than that of X-cells. With the stimulus at the null position, X-cells had an unmodulated discharge rate which was significantly higher than maintained activity, while the firing rate of Y-cells was lower than maintained activity. With the stimulus placed at an eccentric position in the receptive field, X-cells responded in a sustained manner, while Y-cells respond transiently. Because of these observations, we conclude that X-cells correspond to the sustained cells, while Y-cells correspond to the transient cells.

Animals↗