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Biomedical subjects

V G Tsyplenkov

Publications and source records attributed to V G Tsyplenkov.

At least 19 recordsLinked to original sources
PubMed1987

[Effectiveness of radio- and chemoradiotherapy of stage I-II Hodgkin's disease in children].

The paper is devoted to a comparative assessment of the efficacy of radiation and multimodality therapy of stage I-II Hodgkin's disease in children. The authors analyzed therapeutic results in 2 groups of patients with relation to therapeutic programs. The 1st group (58 patients) received radiation therapy after a radical program, the 2nd group (64 patients) received chemoradiotherapy. Comparing immediate and long-term therapeutic results and the results of a recurrence-free course, a conclusion was made of the advantage of multimodality therapy of local-regional stages of Hodgkin's disease in children.

Adolescent↗
PubMed1984

[Radiotherapy in the combined treatment of malignant tumors of the orbit in children].

A study of the long-term results of treatment of 66 children with eye socket tumors has shown that use of a dose over 50 Gy in the postoperative period causes the development of radiation injuries of the facial skeleton and healthy eye. To lessen radiation exposure of the healthy organs and tissues it is advised that intracavitary radiotherapy should be used after eye socket exenteration. The use of this method makes it possible to deliver a necessary dose of irradiation to a focus of lesion with a 2-fold decrease in radiation exposure of the surrounding tissue.

Adolescent↗
PubMed1984

[Evaluation of the efficacy of radiotherapy in the combined treatment of generalized Hodgkin's disease in children].

An analysis of the results of treatment of 108 patients with Hodgkin's disease, Stage III, has shown a high efficacy of multiple modality treatment in children followed-up for 5 yrs. A comparative analysis of the results of the therapeutic programs (2 groups of patients) has shown advantages of the therapeutic program using COPP or CVPP chemotherapy programs for inducing remission which when combined with splenectomy and radiotherapy makes it possible to achieve 5-year survival in 86.6% of children.

Adolescent↗
PubMed1983

[Prognostic significance of a morphological variant of lymphogranulomatosis in children].

An analysis of the clinical data on 183 children who were treated for Hodgkin's disease, and and 7-year follow-up have shown that the determination of a morphological variant is an indispensable part of clinical diagnosis. However prognosis, long- and short-term results depend not on a morphological variant but on the degree of dissemination of a pathological process by the time of the initiation of treatment.

Adolescent↗