Effect of extracorporeal low-density lipoprotein elimination on circulating cell adhesion molecules in patients with hypercholesterolemia.
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Biomedical subjects
Publications and source records attributed to V Gläser.
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UNLABELLED: A case report demonstrates a possibility of successful treatment in a patient with high-dosage phenprocoumon intoxication. CONCLUSION: The use of plasmapheresis is an appropriate method to treat phenprocoumon-intoxicated patients by exchange of endogenous with supplied fresh frozen plasma.
In 20 patients analyses of the coagulation potential were performed in order to test the heparin dosage during chronic hemodialysis. The activated PTT is the most suitable laboratory test. Because of the individually different heparin consumption the control of PTT should performed in every dialysis patient after 90 minutes during the first 2-3 dialysis treatments. Thereby a lasting dosage schedule for each patient could be obtained. The heparin consumption per dialysis unit was approximately 5,200 (3,000-9,000) IU.
One patient with Bartter-syndrome and two patients with pseudo-Bartter-syndrome in abuse of laxatives and diuretics, respectively, were examined clinically and biochemically. The causes of the severe disturbances of the electrolyte metabolism are demonstrated. The differential diagnosis between Bartter- and pseudo-Bartter-syndrome is discussed, exact investigations of electrolyte balance of intake and output are decisive. In consequent therapy with prostaglandin inhibitors (indomethacin), aldosterone antagonists (verospirone) and oral electrolyte supply the prognosis of the Bartter-syndrome is favourable. Little successful is the treatment of the pseudo-Bartter-syndrome. On account of the severe psychic disturbance of the personality a renunciation of laxatives and diuretics, respectively, is frequently not to be achieved.
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The case in question of the Sharp-syndrome is a mixed collagenosis with symptoms of sclerodermia, Erythematodes visceralis, dermatomyositis and rheumatoid arthritis. Apart from the clinical symptomatology the immunological profile is decisive for the ascertainment of the diagnosis. With the help of 3 descriptions of cases is referred to a frequent participation of the kidneys, particularly histologically and immune-histologically. In contrast to the hitherto existing publications also in missing pathological findings of the urine a renal biopsy should be aspired to, since important therapeutic and prognostic considerations are dependent on this.
In the Sharp syndrome we have to do with a mixed collagenosis with symptoms of sclerodermia, erythematodes visceralis, dermatomyositis and rheumatoid arthritis. Above all are observed a Raynaud syndrome, polyarthritis and polyarthralgias, swellings of hands and fingers and myositis and myalgia, respectively. For the ascertainment of the diagnosis as independent picture of a disease the immunological profile is decisive. On the basis of three casuistic cases the author adopts a definite attitude to the Sharp syndrome as independent immunopathy. Questions of diagnostics, therapy and prognosis are discussed.
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In this paper a case of hyperlipaemic arthropathy with participation of the skin in primary hyperlipoproteinaemia type IIa after Fredrickson is described. The case in question is a clinical picture which is very rarely described. Questions of differential diagnosis and genesis are discussed. The prognosis is to be estimated favourably when the basic disease is recognized and treated. The genesis of the disease is not yet clear. With the help of literature several possibilities of the development are discussed.
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In altogether 205 patients with euthyroidism, hyperthyroidism and hypothyroidism the QKD-time was determined. With the help of this examination should be tested whether by means of this simple functional test of the cardiac circulation indirectly is possible also a judgment of the function of the thyroid gland. Essentially in the calculated mean values a differentiation between euthyroidism, hyperthyroidism and hypothyroidism could be made statistically. Since between the individual groups considerable overlappings of the individual values occur the exactness of the test is very much restricted in the preliminary diagnostics of diseases of the thyroid gland. We are of the opinion that the QKD-time is insufficient for the judgment of the function of the thyroid gland.
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A 33-year-old gravida 6, para 5, developed acute fatty liver of pregnancy at 35 weeks' gestation. This clinical picture was seen after caesarean section and delivery of a healthy infant. Post partum hepatic dystrophy associated with coma hepatica, acute renal failure and disseminated, intravascular coagulation was successfully treated with three large-volume plasmaphereses using FFP exchange plasma in combination with haemodialysis. The patient survived and her liver function was restored to normal.