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Biomedical subjects

V Grigorov

Publications and source records attributed to V Grigorov.

13 recordsLinked to original sources

[Blood loss in the placental period in relation to the type of prophylaxis].

The aim of this study is to asses the blood loss in third period of labor according the method of its prophylactic. The material consist of 144 prospective and 192 retrospective cases. The blood loss is assessed visually and after that it is weighted. Up to the delivery of placenta the visually assessed blood loss is insignificantly greater than the weighted one. All cases are subdivided in three groups according the management of third period: -with methergin, with oxytocin and without uterostonic. The blood loss associated with the separation and delivery of the placenta is not different in the groups, but the early postpartum haemorrhage is significantly greater in the cases without uterostonics for the delivery of placenta. In premature labors the blood loss associated with the separation of placenta is significantly greater that in term labor.

Analysis of Variance↗

[Holter diagnosis of the cardiac biorhythm in young persons].

The cardiac biorhythm was studied in 30 young persons 17-28 years of age. Holter's technique for a 24 hour ECG recording was used. In 15 persons the arterial pressure was recorded simultaneously. Supraventricular and ventricular extrasystoles were found and in one person preventricular tachycardia during sleep was recorded. Bradycardia of 34. min-1 was recorded in one person and bradycardia below 40. min-1 during sleep without accompanying rhythm and conduction disturbances was recorded in 30% of the examined persons. No pathologic variations of the arterial pressure were found. An attempt is made to find out correlations between the ECG changes and the activity of the sympathetic/parasympathetic system.

Adolescent↗

[Determination of the specific gravity of the urine using a refractometer].

A method is proposed for urine specific gravity determination by urine refractometric index reading. Only two-three drops are required. Abbe refractometer is used. The urine specific gravity is determined by the formula: (formula: see text), where y = urine specific gravity, x = the refraction read. The method could not be used in cases with glucosuria and ketoniria as well as in case of a considerable proteinemia. The author's results correlate with the results of some foreign authors.

Humans↗

Myocardial viability--mechanisms of reversible myocardial dysfunction and diagnosis in coronary artery disease.

The natural history of ischaemic myocardium and numerous revascularisation studies have proved that it is clinically important to distinguish viable but dysfunctional myocardium from irreversibly injured muscle in patients with coronary disease. A large variety of invasive and non-invasive methodologies are available for the detection of myocardial viability. This review focuses on the value and limitations of the current diagnostic approach to the recognition of stunned and hibernating myocardium in the light of the current understanding of their pathophysiological mechanisms.

Coronary Artery Disease↗

Congenital left ventricular aneurysm in an adult.

A rare case of idiopathic massive apical ventricular aneurysm in a young man is reviewed. Secondary infection was present in the aneurysm. No features of left ventricular failure were observed.

Adult↗

Platelet glycoprotein IIb/IIIa receptor blockade with integrilin (eptifibatide) for early postinfarction angina in a patient with coronary arterial ectasia.

A middle-aged male with multivessel proximal coronary ectasia presented with thrombosis-related acute myocardial infarction and early postinfarct angina, and was successfully treated with a combination of intravenous integrilin (eptifibatide) and unfractionated heparin. The possible aetiology, prognosis and available management strategies are discussed.

Adult↗

Transoesophageal atrial pacing stress echocardiography in coronary artery disease: role, principles and methodology.

This article reviews the physiology and methodology of transoesophageal atrial pacing stress echocardiography (TAPSE) and clarifies its place among the other stress modalities. TAPSE correlates well with myocardial perfusion stress scintigraphy and coronary angiography and is a simple and safe diagnostic option for patients with suspected or known CAD, including those with recent myocardial infarction. Furthermore, the results of TAPSE have prognostic significance in patients with uncomplicated MI. Although, it is a highly feasible and safe technique, the cardiologist should be directly involved in the procedure and the personnel must be well trained in a large number of tests, as for any other stress echocardiographic modalities.

Cardiac Pacing, Artificial↗

Cardiovascular complications of acute cocaine poisoning: a clinical case report.

We present a case of an accidental cocaine overdose with various cardiovascular and neurological complications and ECG features of Brugada syndrome. It is imperative that clinicians know how to recognise and manage the symptoms of cocaine overdose because of the exceedingly rapid progression of the 'cocaine reaction' to a fatal outcome.

Acute Disease↗

A two-year, single-group experience with rotational atherectomy.

Rotational atherectomy was introduced with a view to approaching percutaneously, cases that were suboptimal or unsuitable for conventional percutaneous transluminal coronary angioplasty (PTCA). In this article we present our findings for a period of two years starting in April 2001, when 60 procedures were performed on 54 patients. We found the procedure to be successful in B2 and C type lesions. It is our opinion that the lower burr-to-artery ratio used in our cases was significantly beneficial in decreasing immediate complications related to the procedure. Complimentary PTCA and stenting improved the angiographic end result. Using this strategy, we have achieved very acceptable clinical results.

Aged↗