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Biomedical subjects

V Gualandri

Publications and source records attributed to V Gualandri.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Prenatal diagnosis of a case of familial recurrence of unilateral diaphragmatic agenesis].

Prenatal diagnosis of different fetal malformations have been performed by echography. The authors report a case of recurrence of monolateral diaphragmatic agenesy in sibs. The diagnosis was achieved at the 23 degrees week of gestation. Some methodological details are also proposed to improve the possibility of early diagnosis. Embryological and epidemiological data have been evaluated.

Adult↗
PubMed1983

[Glucose-6-phosphate dehydrogenase deficiency among the student population of Milan].

In our Department a yearly screening is carried out on the school population of Milan, in order to detect beta-thalassaemic trait carriers and G-6-P-D deficient males. This report deals with the results obtained on a group of 21,118 males. They all showed very low enzyme activity and often just detectable; the fall of GSH after incubation with acetylphenhylhidrazine appeared significantly greater than normal. Only 3 cases of hemolytic crises by fava beans ingestion and 7 cases of neonatal jaundice resulted from anamnestic data.

Adolescent↗
PubMed1982

Erythrocyte superoxide dismutase, catalase and glutathione peroxidase in glucose-6-phosphate dehydrogenase deficiency.

Glucose-6-phosphate dehydrogenase (G-6-PD) deficient erythrocytes are particularly sensitive to oxidant stress. In order to evaluate if these cells are protected against oxidant damage, we assayed the antioxidant enzymes superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH-Px) in erythrocytes of G-6-PD deficient (hemizygous and heterozygous) subjects. Normal levels of antioxidant enzymes were found in all subjects examined both with positive and negative histories of haemolytic crisis after fava bean or drug ingestion. In contrast, high levels of catalase and GSH-Px were found in a small group of G-6-PD deficient subjects (hemizygous and heterozygous) with beta-thalassaemia trait, probably by reason of the chronically enhanced oxidant stress which is present in beta-thalassaemia.

Adolescent↗
PubMed1975

[ABO blood-group phenotypes and pathogenesis of cardiovascular diseases. Congenital, rheumatic and coronaric heart disease and arterial hypertension (author's transl)].

Many cases of cardiovascular diseases have been examined in reference to the distribution of ABO blood-groups, in order to calculate the relative risk of disease and the hemogroupal distributive significance in our samples as related to those of other authors, using combined calculation. The analysis concerned the following cases: 746 with arterial hypertension, 3258 with congenital heart disease, 4503 with articular rheumatism, 1047 with acquired valvulopathia, and respective controls. It was found that blood-group phenotypes represent an important biophysiopathological action in regard to articular rheumatism and its cardiac consequences, in myocardial infarction and in hypertension, males only. On the contrary, no action in regard to congenital heart disease was found, with the exception of some single anomalies which have yet to be confirmed. This hemogroupal action greatly exceeds the one limited to the immunitary analogy and is a noticeable part of family heredity. It shows itself in: -- a significant negative association with group O and positive association with group A in the myocardial infarction; -- a significant negative association with group O and positive for the others in the valvulopathic (rheumatic) diseases; -- a positive association with A phenotype and negative with B in arterial hypertension, males only; -- no association with ABO blood-groups and congenital heart disease.

ABO Blood-Group System↗