PubMed Health⌕ Search

Biomedical subjects

V H Escobar

Publications and source records attributed to V H Escobar.

6 recordsLinked to original sources
PubMed1983

Classification and genetics of numeric anomalies of dentition.

A suggested classification of numeric anomalies of teeth is a trimodal classification: anodontia, hypodontia, and hyperdontia. A subclassification into nonsyndromic and syndromic cases would allow for uniform analysis. The limited data on anodontia and hyperdontia have made the genetic analysis of these anomalies difficult. The most suitable data for analysis on the genetics of numeric anomalies of dentition are on hypodontia. A reevaluation of this data, as presented in this report, suggests hypodontia follows an autosomal dominant mode of inheritance. However, the fact that penetrance is not complete suggests the presence of a mechanism whereby epistatic genes interfere with the phenotypic expression of the hypodontia gene. How this occurs is uncertain, but the available evidence suggests a major single gene defect, which is modified by genetic or environmental factors.

Anodontia↗
PubMed1981

A clinical, genetic, and ultrastructural study of snow-capped teeth: amelogenesis imperfecta, hypomaturation type.

Snow-capped teeth (SCT) is a rare form of amelogenesis imperfecta, hypomaturation type. It has been alluded to on numerous occasions but, to our knowledge, no pedigree or clinical-histopathologic data have been published. In this report, two families are described. Scanning electron microscopic (SEM) studies of unetched teeth from affected persons revealed numerous defects of the enamel surface. After etching with 10 percent hydrochloric acid for 21/2 minutes to remove the outer prismless layer of enamel, SEM features of the enamel prism were essentially identical to those of normal teeth. These findings suggest that the structural defect in SCT is confined to the outer prismless enamel layer and that the bulk of the enamel is normal. The genetic analysis supports the concept that SCT is inherited in an X-linked recessive fashion and not as an autosomal dominant trait, as previously reported.

Adolescent↗
PubMed1981

Symmetrical gingival fibromatosis.

Symmetrical gingival fibromatosis, a rare and unusual form of idiopathic gingival fibrous hyperplasia, has recently been identified as a distinct clinical entity. The clinical and histologic features of a case of this disorder are presented. The relationship of this clinical entity to generalized gingival fibromatosis is considered, and the histologic findings in the present case are discussed.

Connective Tissue↗