STUDIES ON THE EFFECT OF TRYPAN BLUE IN THE PREGNANT ARMADILLO, DASYPUS NOVEMCINCTUS.
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Biomedical subjects
Publications and source records attributed to V H FERM.
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Intravenous injection of H-1 virus into pregnant hamsters early in gestation produces an embryocidal and teratogenic effect. The congenital malformations, the presence of inclusion bodies in the fetuses, and the fact that the maternal animals are not affected by this virus, are points of similarity to the teratogenic effects of rubella virus and cytomegalic-inclusion disease virus in man.
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Intravenous injection of vinblastine or vincristine, two antitumor chemotherapeutic agents used in humans, into pregnant golden hamsters on the 8th day of gestation, causes an increase in the fetal mortality rate and the appearance of a significant number of congenital malformations in the surviving fetuses.
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