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Biomedical subjects

V H Frankel

Publications and source records attributed to V H Frankel.

At least 55 records · Page 3Linked to original sources

Biomechanical evaluation of anatomic reduction versus medial displacement osteotomy in unstable intertrochanteric fractures.

The biomechanical characteristics of anatomic reduction versus medial displacement osteotomy were compared for four-part intertrochanteric fractures experimentally produced in cadaver femurs. Eighteen pairs of femurs were assigned randomly to either the anatomic (A) or the medial displacement (MD) group and instrumented with multiple strain gauges. The femurs in the MD group were tested while intact and following four-part fracture with fixation. The femurs in the A group were first tested intact, followed by a stable two-part fracture with fixation, and then by a four-part fracture with fixation and perfect reduction of the posteromedial fragment (PMF) with a lag screw, partial reduction of the PMF, and with the PMF omitted. All fractures were fixed with a 135 degrees, four-hole, sliding hip screw. The strain distribution in the MD group changed significantly after fracture. The plate tensile strain increased by 360% while the compressive calcar strain decreased 85%. The plate tensile strain in the A group also increased significantly after four-part fracture when the PMF was perfectly reduced (160%), partially reduced (290%), or discarded (275%); the calcar compressive strains for these subgroups decreased approximately 50%. This laboratory study indicates that anatomic reduction of four-part intertrochanteric fractures with the sliding hip screw, regardless of the presence or position of the PMF, provides significantly higher compression across the calcar region and significantly lower tensile strain on the plate than fractures reduced by medial displacement osteotomy. The more physiologic strain distribution and the increased medial load transmission support the use of anatomic reduction for the treatment of unstable intertrochanteric fractures.

Biomechanical Phenomena↗

Difficult acetabular revision. A preliminary report.

Thirteen patients (14 hips) underwent revision from conventional cemented total hip arthroplasty to uncemented acetabular threaded screw-in components and cementless femoral press-fit stems by means of the Autophor, Biofit, and Ti-Thread designs. The patients suffered from all forms of primary hip disease except rheumatoid arthritis; their average age was 34 years. The average preoperative Harris hip score was 39.4; the average postoperative score was 71.2 at six months, 90.6 at one year, and 91.6 at two years. Complications included two femoral shaft fractures, one femoral nerve palsy, and one dislocation. No signs have been observed of loosening or migration as of an early (6-24 months) follow-up.

Acetabulum↗

Biomechanics of the hip joint.

A great deal of biomechanical research remains to be done in the area of hip joint trauma so that bioengineers and other medical scientists can work with accurate bone failure data, which are essential to the design of sports equipment, vehicles, workplace situations, and prostheses. The application of biomechanical data, in addition to being essential in prosthesis design and ergonomics, also can be useful in such diverse problems as pathogenesis of degenerative joint disease, management of the postfracture patient, bracing in Perthes' disease, and in many other pathologic conditions.

Adult↗

Telemetering in vivo loads from nail plate implants.

A system of multi-channel telemetry capable of broadcasting in vivo loading from orthopaedic implants is presented. Its use to monitor the two orthogonal bending moments about the nail plate junction of three implanted hip nails is described. Typical results from these cases in which the telemeterized implant was employed to treat proximal femoral fixation and osteotomy are given.

Biomechanical Phenomena↗

Bicycle-related accidents and injuries in a population of urban cyclists.

To gain a better understanding of urban bicycle-related accidents and injuries, 93 Manhattan cyclists were asked to fill out a questionnaire on the subject and the results of their responses were analyzed. They reported a total of 51 bicycle-related accidents and 59 injuries of varying degrees of severity. Although 42 percent declared they used safety helmets, head trauma was reported by 25 percent of the injured cyclists. Most were not wearing protective headgear at the time of their injury, however. Increased cycling mileage and length of time cycling were significantly associated with increased accident occurrence. Surprisingly, 47 percent of the accident victims cited themselves as being at fault for the accident in which they were injured.

Accident Prevention↗

Biomechanics of pathologic fractures.

The successful treatment of a patient with a tumor involves an estimate of weakening due to the tumor and a consideration of the probability of gross fracture through that defect. Weakening due to an open section defect usually results in fracture. Holes produce a stress concentration that is of concern to the orthopedist in reconstituting such fractures. The reconstitution itself must be such that the postoperative possibility of refracture is minimized. Surface-structured intramedullary devices and polymethylmethacrylate offer conversion of open sections into closed sections and minimize the stress risers to allow significant uniaxial bending and torsional loads to be carried by the reconstituted bone, which is usually of inadequate quality to allow reconstitution with screws, plates, and cement. Treatment of a pathologic fracture often involves extensive bony resection, necessitating reconstitution for mechanical stability and reduction of limb shortening. Several combinations of polymethylmethacrylate bone cement and standard metallic devices are satisfactory for reconstitution. Those combinations that offer the maximum cement-metal interface interactions should be chosen and used with proper cement preparation and delivery.

Animals↗

Fatigue behavior of adult cortical bone: the influence of mean strain and strain range.

Uniaxial fatigue tests were conducted of devitalized cortical bone specimens machined from human femora. Specimens were tested at strain ranges from 0.005 to 0.010 under physiologic loading rates. The influence of compressive, zero, and tensile mean strains on fatigue life and on the stress/strain histories during fatigue were examined. Results showed that bone fatigue is a gradual damage process accompanied by a progressive increase in hysteresis and a loss of bone stiffness. The total number of cycles to fatigue failure was influenced only by the total strain range and was not affected by mean strain. Bone was shown to have extremely poor fatigue resistance. Fully reversed cyclic loading to one half of the yield strain caused fatigue fracture in 1000 cycles. Biological implications. The bone regions which experience the highest strain ranges in vivo generally have a compressive mean strain. The results of this study indicate that mechanical fatigue damage accumulates more rapidly in these "compressive" areas than in "tensile" areas of bone.

Aged↗

In vitro evaluation of the loosening characteristics of self-tapped and non-self-tapped cortical bone screws.

The heads of self-tapping and non-self-tapping screws in dog femurs were exposed to a cyclic shearing force of 110 N for 200 loading cycles. This cyclic shear loading created a decrease in pull-out strength for both screw types of approximately 11% (p less than 0.01). No statistically significant difference in pull-out strength was found between screw types either before or after cyclic loading. A linear relationship between pull-out force and cortical thickness was observed for both screw types. These tests corroborated past work which showed equal holding power for the self-tapping and non-self-tapping screw. The progressive loosening of the screws with cyclic shear loading was accompanied by increasing load-displacement hysteresis and screw head migration. Greater hysteresis suggested that the non-self-tapping screw might have loosened more than the self-tapping screw from this applied loading schedule. Bone microcracking around screw threads before and after cyclic loading was observed by scanning electron microscopy. Photomicrographs of one non-self-tapping screw type and two self-tapping screw types showed microcracks at the tip of the outer diameter of the screw thread. More microcracks were observed after application of cyclic shear loading.

Bone Screws↗

Problems associated with tibial fractures with intact fibulae.

Of twenty-three patients more than twenty years old who were treated for a tibial shaft fracture without a concomitant fibular fracture, six (26 per cent) had delayed union or non-union and six (26 per cent) had varus malunion of the fractured tibia. Pain and roentgenographic changes developed in the ipsilateral ankle within two years of injury in two of these six patients with malunion. Of forty-five patients less than twenty years old with similar fractures, one had delayed union and twelve (27 per cent) had varus malunion. Pain in the ipsilateral ankle was observed in two of these twelve patients with malunion. In addition, a bent fibula was observed in thirteen patients who incurred their fractures when they were less than twenty but in no patients who were more than twenty years old at the time of fracture. Clinical observations were corroborated by biomechanical studies on an experimental model. These studies suggested that when the fibula remains intact, a tibiofibular length discrepancy develops and causes altered strain patterns in the tibia and fibula. These may lead to delayed union, non-union, or malunion of the tibia with the sequelae of joint disturbances. The lower incidence of complications in patients less than twenty years old may be due to the greater compliance of their fibulae and soft tissues.

Adolescent↗

Biomechanical study of the pitching elbow.

Medial-tension injuries of the pitching elbow are well recognized. One contributing factor is the extreme valgus which has been noted to occur during the acceleration phase of throwing. It is hypothesized that breaking pitches generate higher medial loading because of the pronation and supination required to impart spin to the ball. The pitching motion is a complex action of all body segments to produce maximum linear and angular acceleration of the ball. The purpose of this study was to correlate elbow loading with pitching style. We measured the forearm segment for axial and tangential (varus-valgus plane) acceleration using accelerometers attached to the forearm and hand. Muscle activity was measured by EMG. Forearm rotation was assessed by stroboscopic photography. Despite different delivery styles when throwing breaking pitches, each pitcher demonstrated patterns of muscle activity and acceleration which were similar. Deceleration forces were lower than acceleration forces. Pronation and supination were documented and contribute to the direction of ball spin. Accelerometers can be used to evaluate pitching mechanics. We suggest that the main factors causing an elbow injury are the amount of throwing and the force with which the ball is thrown.

Baseball↗

Meniscal regeneration and postmeniscectomy degenerative joint disease.

The failure of meniscal regeneration via a fibrous semilunar mold can be correlated with an increased incidence of degenerative joint disease. Experiments on rabbits revealed a statistically significant relationship between the failure of meniscal regeneration and the development of degenerative joint disease, characterized by osteophyte formation, cartilage pitting and erosions, and loss of carbilage proteoglycan. Similar results in limited studies utilizing adult fox hounds supported this observation. In dogs, variation in the extent of tissues resected about the meniscus, including synovectomy, did not inhibit the reformation of a fibrous semilunar mold. No specific "zone of regeneration" responsible for meniscal regeneration was identified.

Animals↗

Fibrous contracture of muscles following intramuscular injections in adults.

Periarticular fibrous muscle contractures in adults from repeated injections in the same site is predictable. The causes of joint contracture in children are many and complex, but in adults it seems certain that this phenomenon is the result of repeated injections of analgesics or other agents into 1 muscle area. Any drug if repeatedly injected locally may cause fibrosis of the muscle and subsequent joint contracture. Five cases of bilateral abduction contracture of the shoulder in adults including the first case of bilateral abduction contractures of shoulder and hip plus bilateral flexion contracture of elbow and extension contracture of a knee are reported. No underlying disease which might predispose to this fibrosis of muscles was noted. The frequency and period of injections were variable over several years. In all patients the interference in activtities of daily living were serious, but the deformities were corrected by release of the fibrous band with relief of discomfort and restoration of joint motion without recurrence. Noting the potential complication of repeated intramuscular injections in one area, this practice should be avoided whenever possible in adults, as well as in children.

Adult↗