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Biomedical subjects

V H Jotterand

Publications and source records attributed to V H Jotterand.

3 recordsLinked to original sources

Ultrasonographically guided injection of corticosteroids for the treatment of retroseptal capillary hemangiomas in infants.

PURPOSE: Injection of corticosteroids is a well-documented and successful mode of treatment for periorbital capillary hemangiomas. Because of the greater potential risk involved with retrobulbar injections, no prior study has described this treatment for tumors located behind the orbital septum. Although retroseptal intraorbital capillary hemangiomas comprise only 7% of all adnexal capillary hemangiomas, complications such as optic nerve compression or astigmatism may necessitate treatment. METHODS: Three patients with deep orbital hemangiomas that caused vision-threatening complications were treated with intralesional injections of triamcinolone and betamethasone. Orbital injection was performed with use of real-time ultrasonographic guidance of the needle. This technique was valuable in providing continuous, accurate, and safe advancement of the needletip in the orbit to avoid the globe and orbital walls. Ultrasonography also permitted precise placement of the needle tip within the tumor and visualization of the injected material. RESULTS: Significant improvement was demonstrated in all cases on the basis of both ultrasonographic measurements and regression of clinical manifestations such as astigmatism, chemosis, proptosis, and optic nerve pallor. No complications were noted. CONCLUSION: Intralesional injection of corticosteroids to treat retroseptal and retrobulbar capillary hemangiomas was found to be a safe and effective treatment modality in our patients. Positioning of the injecting needle was guided by ultrasonography.

Adrenal Cortex Hormones↗

Enhancing surgery for acquired esotropia.

In acquired esotropia, operating only on the non-accommodative angle often results in undercorrection. To decrease the frequency of this outcome, we enhanced surgery in a preliminary study by operating for a target angle equal to half the sum of the distant non-accommodative angle (minimum 12 prism diopters) plus the distant angle measured without correction. The mean augmentation in 12 patients undergoing bimedial rectus recession was 0.8 +/- 0.2 mm, and in eight patients who had a previous bimedial rectus recession and were undergoing a bilateral rectus resection it was 1.7 +/- 0.8 mm. With a mean follow-up of 26 +/- 20 months, 13 patients were within 10 prism diopters of orthotropia and four were undercorrected. Three overcorrected patients were orthophoric after reducing the hyperopic correction. All 17 patients old enough to cooperate had stereopsis or a positive Worth four-dot test at some point postoperatively.

Child↗

Metastatic Pseudomonas endophthalmitis following bronchoscopy.

Symptoms of uveitis developed in the left eye of a 61-year-old woman 2 weeks after bronchoscopy to investigate hemoptysis. The true diagnosis of metastatic endophthalmitis was unsuspected for 1 month. Both sputum and vitreous samples yielded Pseudomonas aeruginosa when cultured. Despite aggressive medical treatment, subtotal vitrectomy and intraocular injections of antibiotics, enucleation was eventually necessary. To our knowledge this is the first reported case of metastatic endophthalmitis following bronchoscopy. It is also the first report of the concentration of ceftazidime pentahydrate in the vitreous humour of an infected human eye.

Bronchoscopy↗