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Biomedical subjects

V Henry

Publications and source records attributed to V Henry.

8 recordsLinked to original sources
PubMed1995

Effects of age and endurance training on beta-adrenergic receptor characteristics in Fischer 344 rats.

The purpose of this investigation was to examine changes in beta-adrenergic receptor characteristics in various tissues with age and endurance training. Forty-eight young (6 months), middle-aged (15 months), and old (25 months) male Fischer 344 rats were assigned to either a trained or sedentary running group. Animals were endurance trained by 10 weeks of treadmill running at 75% maximal capacity, 1 h/day, 5 days/week. Animals were sacrificed at rest and the heart, liver, and soleus were removed for analysis. Percent of high and low affinity binding sites were determined by competitive binding experiments. Competition curves were generated using 12 concentrations of ICI-89406 (beta 1 antagonist) and ICI-118551 (beta 2 antagonist) to inhibit the total binding of (-) [125I] pindolol (IPIN). Maximal binding site number (Bmax) and affinity (KD) were determined by Scatchard analysis. Heart Bmax did not differ with age or training. An aging effect was observed in liver such that middle-aged and old animals had greater Bmax compared to young animals. In soleus, Bmax was not altered with training but decreased with age. While training had no affect on affinity in the liver and soleus, heart affinity increased with training in both the middle-aged (21%) and old (27%) animals. In soleus, affinity increased but remained unaltered in heart and liver with age. The ratio of beta 1:beta 2 receptors in the heart and liver did not differ with age or training. The influence of age and training on beta-adrenergic receptor characteristics appear to be tissue specific.

Aging↗
PubMed1992

Collaboration: integrating practice and research in public health nursing.

The need to integrate clinical practice and research has been stressed for many years in both public health and nursing. This article describes such a collaborative project between two rural upper Midwest public health nursing agencies and public health nursing faculty from a small, liberal arts, baccalaureate nursing program. The high-risk prenatal research project provided an opportunity for nursing staff and faculty research consultants to work together on a clinical study. A model for collaborative research is illustrated, and advantages and disadvantages for practice, administration, and research are discussed.

Clinical Nursing Research↗
PubMed1989

[Neonatal adrenoleukodystrophy. Apropos of 3 cases in siblings].

Neonatal adrenoleukodystrophy is a recently individualized disease manifested by very early onset of neurologic deterioration. Progression of the disease is rapid and there is no effective therapy. Differences with X-linked adrenoleukodystrophy include genetic inheritance, which is autosomal recessive, a more severe prognosis, and presence of multiple peroxisome enzyme deficiencies that justify classification alongside the Zellweger syndrome among the peroxisome disorders. We report three cases in siblings and describe the main clinical and biochemical features.

Adrenoleukodystrophy↗
PubMed1982

The relationship of amniotic fluid phosphate-to-zinc ratios to post-cesarean section infection.

Although many reports concerning risk factors for post-cesarean section febrile morbidity have been published, few have considered the antibacterial activity of amniotic fluid. This study, in which the amniotic fluid phosphate-to-zinc ratios were used as a reflection of antibacterial activity, demonstrates that, among 85 patients who underwent elective repeat cesarean sections, less febrile morbidity was present when the patient's amniotic fluid had greater antibacterial activity. There was less standard fever, use of antibiotics, and endometritis among patients whose amniotic fluid had lower phosphate-to-zinc ratios.

Amniotic Fluid↗