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Biomedical subjects

V Hermsen

Publications and source records attributed to V Hermsen.

5 recordsLinked to original sources

North Carolina macular dystrophy and central areolar pigment epithelial dystrophy. One family, one disease.

The autosomal-dominant macular dystrophies known as North Carolina macular dystrophy and central areolar pigment epithelial dystrophy were originally described as distinct disease entities in three separate families. However, these disorders have several phenotypic features in common. The single large family with North Carolina macular dystrophy, which descended from three Irish brothers in 1790, has undergone extensive genealogic studies expanding the kindred to more than 2000 family members. As a result, two previously described families with central areolar pigment epithelial dystrophy have been found to descend from these same three Irish brothers with North Carolina macular dystrophy and, therefore, also have North Carolina macular dystrophy. This helps simplify the nosology of the disease and expands the phenotype of North Carolina macular dystrophy to include choroidal neovascular membranes.

Child↗

Rubeosis capsulare.

Two patients with diabetes had extracapsular cataract extraction with intraocular lens (IOL) implantation. Both developed rubeosis iridis and neovascularization within the lens capsule supporting the IOL, a condition we have termed rubeosis capsular. Argon laser treatment was ineffective in both patients. One patient was successfully treated by virectomy with endophotocoagulation. The other patient had a vitrectomy which was followed by a fibrinoid reaction, continued inflammation, rubeosis, and phthisis bulbi.

Cryosurgery↗

Vitrectomy in severe ocular trauma.

This report describes the outcome of 73 consecutive cases of severe ocular trauma that were managed by pars plana vitrectomy and followed for an average of 37 months. 38% of operated eyes achieved a final visual acuity of at least 0.5 (20/40) and 69% obtained 0.025 (5/200) or better vision. These results are similar to other published reports. The final visual acuity in this series proved to be similar in patients who had early vitrectomy (1-14 days) and those who underwent vitrectomy after 14 days. The best results were achieved when vitrectomy was performed between 15 and 30 days following injury. In contrast to other reports no decrease in the final visual result was noted in eyes that had definite blood-lens-vitreous mixing, nor was there evidence of increased fibrovascular ingrowth or a poorer visual prognosis in the 1- to 15-year-old age group.

Adolescent↗

The use of ultrasound in the evaluation of diabetic vitreoretinopathy.

A basic examination of the globe is performed with A-scan ultrasonography, and careful attention is given to the extent of vitreous opacities and areas of high reflectivity. B-scan ultrasonography then is used to delineate the topography of the disorder. A change in the patient's position while scanning may allow liquid blood to flow across the retina so that it can be displayed. Other kinetic clues are used to differentiate opacities in the vitreous from liquid blood on the retina, fibrovascular membranes, and retina itself. Finally, A-scan quantitation is used again to differentiate fibrovascular membranes from retinal detachment and the posterior surface of the posterior vitreous detachment. A careful sketch of the pathological condition is made for use in monitoring the patient or at vitrectomy.

Diabetic Retinopathy↗