[In vitro antibacterial effect of sulfamoxole/trimethoprim and sulfamethoxazole/trimethoprim].
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Drug Combinations↗
Biomedical subjects
V Hingst
Publications and source records attributed to V Hingst.
[The importance of adhesive dry mats for the reduction of germ spreading in hospitals (author's transl)].
Footwear of hospital staff present a distinct problem for transmission of different germs. According to literature references footmats of synthetic fibres or spun rayons, which are soaked with disinfectants generally do not lead to the required reduction of germs. They should not be used for the prevention of germ dissemination.--Antimicrobial adhesive mats are able to reduce the number of infectional bacteria from the soles of clean staff shoes to almost 50 percent of the former amount. In addition they kill the adhesive bacteria by an impregnated disinfectant.--With normal soiled shoes, however, the mats show a rapid descrease of adhesive capacity. Moreover such contaminated mats could develop into a source of bacteria.--Therefore, adhesive mats should only be used in areas of marked cleanliness. Also, from an economical point of view, the regular use of these mats can be propagated in these areas only.
Bacillus subtilis↗
Elimination of Staphylococcus aureus in hemodialysis patients.
Staphylococcus aureus infection and its complications are of great concern in the care of hemodialysis patients. Nasal contamination with S. aureus seems to be the main source of cutaneous contamination. The decontamination and recontamination of the skin of hemodialysis patients after using mupirocin nasal ointment was followed in a placebo control study. After 10 days of therapy with mupirocin nasal ointment, 25 of 33 (73%) patients were free of nasal S. aureus contamination in the nares (control subjects 2 of 21, 10%). At the same time, the prevalence of positive skin cultures for S. aureus decreased from 30 of 33 (90%) to 11 of 33 (33%) patients. However, during the ensuing 130 days, 14 of 25 (58%) patients with negative nasal cultures became recontaminated, while the skin became recontaminated in 11 of 22 (50%) patients. In 10 of 14 S. aureus recontaminated patients the original S. aureus lysotype was documented by specific phage reaction. Four of fourteen patients had a new S. aureus lysotype. Mupirocin nasal ointment eradicated S. aureus transiently in 75% of the patients but continuously in only 11 of 33 (30%) patients.
Administration, Intranasal↗