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Biomedical subjects

V Hurgoiu

Publications and source records attributed to V Hurgoiu.

At least 19 recordsLinked to original sources

The skinfold thickness in preterm infants.

The development of the subscapular, triceps and abdominal (suprailiac) skinfolds was studied in 120 healthy preterm infants with a birth weight below 2500 g at the age of 2 weeks, 1 month and 2 months. The skinfolds developed with the age of the infants, no gestational age related differences being noted. The triceps skinfold was thicker than the subscapular and abdominal skinfolds. The increase of skinfold thickness in identically-fed healthy appropriate-for-gestational-age preterm infants correlated with post-conceptional age. Small-for-gestational-age babies had thinner skinfold thicknesses up to a post-conceptional age of 44 weeks.

Birth Weight

[Supplementation of energy intake in premature infants by parenteral administration of lipids].

Premature infants are at risk for malnutrition and essential fatty acid deficiency. The authors administered 0.5 g of lipids by parenteral route as an adjuvant to enteral feeding, in 30 healthy premature infants aged 14 days to 6 weeks, with a body weight at birth of 1,879 +/- 325 g, presenting a slow rate of weight gain. This led to a long term improvement of the body weight gain preventing malnutrition. The serum level of total triglycerides, cholesterol, phospholipids and glycemia remained within normal limits.

Blood Glucose

Thermal regulation in preterm infants.

The development of thermoregulation was studied in 14 healthy preterm infants with body weights of 1000-2200 g, appropriate for gestational age and conception ages of 32-46 weeks. Tympan, skin and rectal temperatures were measured under the same conditions three times daily for 7 successive days. The body temperature, the temperature of the tympan, the facial and abdominal skin temperatures did not show oscillations during the day. The temperature of the tympan, rectum and skin increased when the ambient temperature rose over 28 degrees C. The tympan temperature increased with age starting from 39 weeks post conception.

Body Temperature

[Mineral composition of the milk of mothers of premature infants during early lactation].

The authors have assessed the concentration of sodium (Na), potassium (K), calcium (Ca), magnesium (Mg), zinc (Zn), copper (Cu), manganese (Mn), lithium (Li), cadmium (Cd) and lead (Pb) in the milk of mothers with premature births, during the first month of lactation. The levels of Na, Cu and Mn were decreased and those of K, Ca, Mg, Zn and Li were unchanged. The needs of Na, Ca and Mn for the premature infants are insufficient. Li, present in all the milk samples at a constant level, seems to be a common component. The incidence of Cd in the milk of 7 mothers and of Pb in 4 milk samples indicates their clearance from the mothers' organism.

Adolescent

[The fat ration for the premature infant].

The authors studied cantitative and calitative fat dietary intake in conditions of isocaloric energetic diets and effects on somatic development and on plasma levels of fats in 3 randomized populations of premature infants. They concluded that dietary intake of 3-6.4 g fats/kg b.w./24 hours permitted a satisfactory somatic development (weight, height, cranial circumference). In conditions of isocaloric energetic diets, levels of fat intake of 3g/kg b.w./24 hours delivered only the energy for proteic syntheses and levels of 5.6-6.4 g/kg b.w./24 hours also permitted the constitution of body deposits. The levels of total lipids and cholesterol were related to the dietary intake of fats. In case of dietary supplementation of linoleic acid, the plasma levels of cholesterol were reduced and the plasma levels of HDL were augmented.

Birth Weight

[The metabolic characteristics of low-birth-weight infants].

The authors studied the protein and fat metabolism in 2-6-weeks-old premature (100 cases) and "small for date" babies (20 cases), all being artificially fed with isocaloric diets. Weight curves were related to dietary intake of proteins in small for date babies. The premature born infants showed no similar relationship between dietary intake of proteins and weight charts. BUN had superior values in premature babies; it means probably that the kidneys of the small for date infants responded better to a protein charge. The values of both serum total fats and of the cholesterol were related to the dietary intake of fats. In conclusion, the milk formula have to be adapted to metabolic peculiarities of these categories of infants.

Dietary Fats

[Hypoplasia of the intrahepatic biliary tract in premature infants].

Neonatal cholestatic disturbances are frequent in premature neonates. An important role in the group of causes which may induce cholestasis is that of hypoplasia of the intrahepatic biliary pathways. Ten cases are described, of prematurely born infants with hypoplasia of the intrahepatic biliary pathways. The children had 980-1,900 g at birth. The diagnosis was made on the basis of the clinical picture, of conjugated hyperbilirubinemia, and of the necropsy findings in 7 of the cases. The incidence and the lethality were high in very small premature infants, in whom compensation responses of the hepatic tissue are rather a particular case. In all the cases the authors noted the presence of malabsorption syndromes, of atrophic enteritis, and a defect in the growth rate.

Bile Ducts, Intrahepatic