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Biomedical subjects

V Husák

Publications and source records attributed to V Husák.

At least 19 recordsLinked to original sources
PubMed1992

Absolute quantitation of gallium-67 citrate accumulation in the lungs and its importance for the evaluation of disease activity in pulmonary sarcoidosis.

Our modification of a method for the absolute quantification of gallium-67 uptake in lungs with a scintillation camera and computer is described. The uptake of 67Ga in lungs, expressed in percentage of administered radioactivity, was determined by the transmission-emission method. We proved theoretically and experimentally that a 67Ga planar source could be replaced with a 57Co planar source. The performance of lung perfusion scans allows a more accurate delineation of the regions of interest on gallium scans. The method was applied to control subjects (n = 27) and to patients (n = 114) suffering from biopsy-proven pulmonary sarcoidosis (28 with inactive and 86 with active disease). The obtained results were compared with chest X-ray findings, the percentage of lymphocytes in the bronchoalveolar fluid (BAF-ly%), and serum angiotensin-converting enzyme (SACE) values. The method seems suitable for the assessment of disease activity in sarcoidosis. It is more accurate in detecting parenchymal involvement in lung sarcoidosis than the commonly used X-ray criteria. No correlation was found between 67Ga uptake and the BAF-ly% and SACE values.

Bronchoalveolar Lavage Fluid↗
PubMed1990

[Activity of administered radiopharmaceutical agents and the radiation burden of the Czechoslovak population caused by nuclear medicine].

The authors assessed by means of questionnaires the activities of radiopharmaceuticals administered in departments of nuclear medicine in Czechoslovakia. The mean activities of individual radiopharmaceuticals are roughly equal as in Great Britain, but lower than in the Canadian province of Manitoba. The differences of activities used in different departments are approximately equal in all compared countries. In the Czech Republic the annual collective effective dose equivalent from nuclear medicine was 433 Sv in 1983 and 609 Sv in 1987. The mean effective dose equivalent per examination was 2.23 mSv in 1983 and 2.44 mSv in 1987. The mean effective dose equivalent per inhabitant of the Czech Republic was 0.042 mSv in 1983 and 0.059 mSv in 1987. The radiation dose of the Czech population from nuclear medicine amounts approximately to one tenth of the load from radiodiagnostics.

Body Burden↗
PubMed1989

[A device for measuring contamination of hands in work places with open radiation sources].

The device manufactured is equipped with the NaI(Tl) scintillation crystal situated in a thick lead shielding. The cavity in the lead shielding allows inserting a hand which is in contact with the detector during the measurements. The apparatus exhibits low values of the minimum detectable superficial activity of radionuclides emitting low energy gamma-rays (e.g. 125I, 99mTc). The apparatus complies with the requirements for a sensitive and prompt monitoring the contamination of hands in departments of nuclear medicine with the numerous staff.

Gamma Rays↗
PubMed1989

[A dynamic phantom for quality control of ventriculography examinations].

The authors designed and constructed device simulating the activity of the heart, based on periodic filling and emptying two rubber blowers a radioactive solution by means of two pistons in cylinders operated by two specially shaped cams. The phantom enables to control the correctness of the method and a computer programme for evaluating parameters of heart activity (ejection fraction, end-diastolic volume, pulse volume etc.) in balanced ventriculography performed by a scintillation camera coupled with a computer. The performed measurements have shown a very good agreement of the evaluated parameters with those set at the phantom. The designed device is of an original construction and was granted the author's certificate No. 238,298.

Heart↗