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Biomedical subjects

V I Bondarev

Publications and source records attributed to V I Bondarev.

At least 19 recordsLinked to original sources
PubMed1995

[The role of anatomical factors in predicting the probability of the development of an abdominal ischemic syndrome].

Anatomo-topographical studies, performed in 100 human corpses established that predispositions to development of the extravasal compressions (EC) of the coeliac trunk (CT) may be observed at high location of the aortal canal mouth, which is usually observed in case of dolichomorphic constitutional type. Complications of not diagnosed coeliac trunk extravasal compressions were the possible reason in 3% of sections. Acute substernal angle (< or = 70 degrees) is an easily determined and significant indicator of dolichomorphic type. This should be taken into account by clinicians in cases of unclear abdominal syndrome.

Abdomen↗
PubMed1995

[Intra-abdominal lavage in the multimodal treatment of patients with acute diffuse peritonitis].

Study showed that the suggested method for appraising the severity of the inflammatory process makes it possible to decide whether peritoneal lavage is necessary in each concrete case. The authors examined 217 patients with acute generalized peritonitis (AGP). Four degrees of the risk of a severe course of AGP were distinguished conditionally. Patients with the first degree of risk do not need intraabdominal lavage. To remove the noted inflammatory changes in the peritoneum it was sufficient to cleanse thoroughly and drain the abdominal cavity and introduce antibiotics into it during complex treatment. Intraabdominal lavage is indicated for patients with the second degree of risk and with marked inflammatory changes in moderate circulatory changes. Abdominal lavage with peritoneostomy is indicated for patients with pronounced inflammatory (N = 3.8 cond. units) and microcirculatory disorders (Y = 0.2 cond. units). Peritoneal lavage is not indicated in patients (third and fourth degrees of risk) with considerable inflammatory (N = 4.04 cond. units) and microcirculatory disorders (Y = 0.4 cond. units).

Acute Disease↗
PubMed1994

[Surgical treatment of diseases of the operated stomach].

Clinical follow-up results of 876 patients with operated stomach malady, 342 of whom were operated on, were analyzed. In 58% of patients after the perforation closure the ulcer recurrence occurred, in 26% after gastric resection--peptic ulcer, in 26%--functional pathological syndrome. Surgical tactics depended on character of previously conducted procedure, general condition and age of the patient, secretory function of stomach and operative situation. Complications occurred in 6.1% of patients. Mortality was 1.2%.

Aged↗
PubMed1994

[Extravascular compression of visceral arteries in the diaphragmatic segment of the aorta].

There were 140 patients operated for the celiac trunk (CT) and renal arteries extravascular compression (FC) in diaphragmatic aorta segment. The clinical syndromes of chronic abdominal ischemia and vasorenal hypertension were depicted. The predisposing factors of CT EC is the patients' dolichomorphic constitution with epigastric angle of < or = 70 degrees. The effectiveness of differentiated tactic choice of operative intervention magnitude according to the disease stage was shown. The late follow-up results witnesses the necessity of timely and adequate treatment.

Abdomen↗
PubMed1993

[Disorders of immune status in duodenal ulcer complicated by perforation and peritonitis].

The chemotaxic activity of neutrophil granulocytes was studied in 112 patients with duodenal ulcer disease complicated by perforation and peritonitis with a different degree of spreading. Sharp decrease in spontaneous migration of leukocytes (SML) was revealed in generalized peritonitis. In diffuse peritonitis, the index didn't differ from that in normal subjects. In patients with the complicated course of the postoperative period, SML stimulation under the influence of the own serum was noted. At day 3-9 after the operation, the stimulating activity of the humoral factors of immunity was gradually decreasing. Use of the stimulators of migrative activity of phagocytes contributes to normalization of their function. In patients who had the immunocorrigative agents been prescribed, aggravation of peritonitis and purulent-septic complications were noted 1.4-fold less often than in absence of such treatment.

Adult↗
PubMed1993

[The therapeutic measures in acute diffuse peritonitis].

Analysis of the observations of 431 patient with acute diffuse peritonitis is presented. Use of intraabdominal flowing lavage is recommended in patients with inflammatory phenomena against the background of moderately pronounced changes in microcirculation in the parietal peritoneum. The maximum clinical effect of hemosorption and lymphosorption was noted at the first 3 days after the operation in cathepsin-D activity in the blood equal to 14-17 activity units/(min.mg) and lymphorrhea over 700 ml/day. Lethality was 18.8%.

Acute Disease↗
PubMed1992

[The use of cholesorption in the treatment of patients with acute cholecystitis complicated by cholangitis].

The results of treatment of 137 patients with acute cholecystitis complicated by cholangitis are presented. The causes and clinical signs, and tactics for operative treatment of the disease are described. Progressive hepatic failure is one of the causes of lethality. Use of the developed method of cholesorption permitted to reduce the incidence of hepatic failure development, decrease postoperative lethality to 9.5%.

Acute Disease↗
PubMed1992

[New approaches in diagnosis and therapy of the thoracic outlet syndrome].

The results of diagnosis and treatment of the thoracic outlet syndrome (TOS) in 35 patients have been analysed. Compression of the subclavicular neurovascular bundle at the site of its outlet from the thoracic cavity was most frequent cause of TOS development. A degree of compression was assessed quantitatively by the data of a modified functional dynamic test. The modified operation, including resection of the I rib (and of a cervical one in its presence), scalene muscle, musculus pectoralis minor, periarterial sympathectomy of the subclavicular artery, was performed. In narrow (less than 1.5 cm) costoclavicular space, the II rib was additionally resected. An excellent long-term result is indicative of the effectiveness of the method.

Adolescent↗
PubMed1992

[Prevention of early inflammatory complications after transthoracic interventions and estimation of the degree of immunologic deficiency].

An analysis of the results of the examination and treatment of 379 patients undergoing transthoracic interventions showed that the use of the target-aimed selective immunomodulation, short-term antibacterial prophylaxis, inhibitors of arachidonic acid metabolites, active elimination of the circulating immune complexes and medium-weight molecular peptides and adequate local analgesia after the interventions providing normalization of the laryngeal reflex and early activation of the patients permitted the incidence of the pulmonary complications to be decreased by 2.5 times, pleural complications by 1.7 times, suppuration of the postoperative wound by 1.8 times and the total expenses by 25.6 per cent.

Adjuvants, Immunologic↗
PubMed1992

[Combined antibacterial therapy in acute lactation mastitis].

The results of treatment of 129 patients with acute suppurative lactic mastitis are presented. In severe forms of the disease, the use of combined antibiotic therapy+ permits to shorten the duration of in-patient treatment from 13.5 to 10.3 days, prevent the disease recurrence.

Acute Disease↗
PubMed1991

[Clinico-morphological characteristics of acute pancreatitis and its complications].

The results of treatment of 6681 patients with acute pancreatitis (AP) were analysed. Operated on were 554 patients with AP, among them, 260-with acute destructive pancreatitis (ADP). Total lethality was 1.6%, the postoperative one-20.2%. In ADP, the postoperative lethality was 28%. Mild forms of the AP course were characterized by constancy of the clinical symptoms and their rapid involution, severe forms of the disease (destructive pancreatitis)--by progressive periodicity and intensity of clinical signs. A morphologic pattern of the different forms of AP is described. It was established that at the early period of the disease, patients died mainly from posthemorrhagic anemia, anemia with intoxication, at the late period--predominantly from different purulent and necrotic complications.

Acute Disease↗
PubMed1991

[Use of external drainage of the thoracic duct and lymphosorption in the complex treatment of acute diffuse peritonitis].

In 47 patients with acute generalized peritonitis in the complex of therapeutic measures, the external drainage of the thoracic duct (EDTD) with subsequent lymphosorption (LS) was used. The effectiveness of treatment was judged about by the lymph and blood toxicity, and as well by contents of peptides with the molecular mass of from 300 to 1000 dalton. In favourable course of the postoperative period, the increase in lymph debit and decrease in proteolytic enzyme activity in the lymph and blood were noted. The use of EDTD and LS in the complex with the other methods of treatment permitted to achieve a clinical effect in 76.6% of cases.

Acute Disease↗
PubMed1990

[Extracorporeal detoxification using heterologous spleen in acute pancreatitis].

The method of extracorporal connection of the swine spleen (ECSS) was used in the complex treatment of 32 patients with acute pancreatitis. Three patients died. It was established that ECSS effectively reduced hyperfermentemia and increased the phagocyte activity of blood leukocytes which was an important component of complex treatment of patients with acute destructive pancreatitis.

Acute Disease↗
PubMed1990

[Disorders of immunoreactivity in acute cholecystitis in middle-aged and elderly patients and their correction in preventing postoperative complications].

In elderly and senile patients with acute cholecystitis, the decrease in the content of T-lymphocytes and their functional activity, number of B-lymphocytes and IgG level, increase in the IgM and IgA content were noted. The attenuation of non-specific protective mechanisms was revealed. In patients, who underwent the purposeful immunocorrection with prodigiosan, proper-myl, methyluracil and staphylococcal adsorbed anatoxin, the number and activity of T-lymphocytes normalized, number of B-lymphocytes increased at the time of operation and after it. This contributed to reduction of the incidence of the inflammatory complications 3-fold.

Acute Disease↗
PubMed1990

[Analysis of mortality in acute diffuse peritonitis].

The causes were studied and the analysis was performed of the lethality in 329 patients with acute diffuse peritonitis (ADP). The incidence of lethal outcome of ADP directly depended on the time of hospitalization, age of the patients, source of peritonitis, and as well on the technique of operative intervention. Progressive peritonitis caused death in 71 (92.2%) of 77 patients.

Abdominal Injuries↗
PubMed1990

[Determination of the activity of lysosomal enzymes in the blood and of the morphometric indices in the peritoneum in acute diffuse peritonitis].

The dynamics of activity of lysosomal enzymes in the blood, morphometric indices in the parietal peritoneum was studied in 217 patients with acute diffuse peritonitis depending on the severity of the process. It was established that patients suffering of acute diffuse peritonitis through showing to a certain extent similar clinical picture differ, however, by their morphochemical indices. Comparing the activity of catepsin-D, relative specific volume of erythrocytes (V), density of distribution of polymorphonuclear leucocytes (N) it may be suggested that catepsin values over 16.9 ast. un (min, mg), V--over 0.4 conv. un., N over 4.04 conv. un indicate irreversible changes in the tissues.

Acute Disease↗