[Local application of several enzymes in the treatment of chronic suppurative otitis media with cholesteatoma].
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Biomedical subjects
Publications and source records attributed to V I Egorov.
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The tensile properties of the intact and sutured human intestine were examined using Instron 1122 tensimeter on 471 cadaveric and 98 surgically removed specimens. By a constant strain rate method two maxima curves were received, which permit examination of the intestinal wall as a multi-layered structure. Repeatable results were generated for cadaveric and surgically removed intestines, whose mechanical properties were similar under certain storage conditions. The mechanical properties of intact intestine in axial and transversal directions were different. The mechanical strength of the intact intestinal wall was conditioned by the submucosa and muscularis, while the serosa and mucosa showed no significant strength. Comparison of axial specimens' mechanical properties of the intact intestinal wall and intestinal wall with all layers sutured through determined that only the submucosa supplies mechanical strength to anastomosis. Other layers contribute no significant force to anastomotic strength. The strength applied to thread during knot tying does not change the participation of the intestinal layers in supplying suture-holding capacity for 8 and 12 mm stitch depth. It was shown graphically why sutures that don't stitch onto the submucosa are unreliable.
In homogenates of rat tissues hydrolysis of O-heptyl-O-orthonitrophenylmethyl phosphonate, O-pentyl-O-orthonitrophenylmethyl phosphonate and O-heptyl-O-isopentyl-O-orthonitrophenylphosphate was studied. Hydrolysis of the preparation was shown to be carried out mainly in liver tissue and slso in kidney and blood serum. The substances studied were cleaved only at the bond P-O-aryl. The structure of orthonitrophenyl phosphoorganic substances exhibited the distinct effect on Km and on the maximal rates of the enzymatic hydrolysis. In all the tisses studied O-heptyl-O-orthonitrophenylmethyl phosphonate was hydrolyzed with maximal rate.
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Non-symbiotic nitrogen fixation was studied in virgin and cultivated podzol soils of the Kola Peninsula by the acetylene and isotope techniques. The activity of nitrogen fixation varied sharply in cultivated soils due to degradation of plant residues and the action of plant root secretion. No significant changes were observed in the activity of nitrogen fixation within the vegetative period in virgin soils. Less than 1 kg of nitrogen per hectare was accumulated in soils as a result of its non-symbiotic fixation during the vegetative periods of 1976--1977.
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