[Vitamin status and spermatogenesis in rats in late periods after irradiation with various doses].
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Biomedical subjects
Publications and source records attributed to V I Erasova.
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Study of reproductive function in simulating experiments is important as for expansion of our theoretical knowledge in the field of gravitational physiology and space biology and for the decision of applied problems in space and clinical medicine. Long-term bed rest in a head-down tilt--6 degrees (BRHDT)--antiorthostatic hypokinesia is a wide spread method for ground-based simulation of space flight's conditions (mainly of hemodynamical effects of microgravity and restriction of locomotor activity). The aim of the present research was to study a reproductive function in males during 60-120 day BRHDT.
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A total of 164 males aged from 22 to 50, who had taken part in liquidating the consequences of Chernobyl power station accident, was examined. According to the military cards irradiation dose did not exceed 25 cGy. Semen of 125 examinees was studied. One third of examinees showed sexual dysfunction, which did not appear to depend on the irradiation dose. Analyses revealed pathologic changes in semen and ultrasound demonstrated alterations in prostate and seminal vesicles similar to chronic prostatitis and vesiculitis. No typical radiation-induced lesions were discovered. The author suggest assigning infertility and impotence to the list of entitles, which occurred and exacerbated due to liquidating the consequences of Chernobyl power station accident.
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We made examinations (physical, clinical and laboratory) of 301 senior children and adolescents with varicocele admitted to Research Institute of Urology for the last 5 years. Spermatogenesis was assessed by WHO criteria for healthy men. 78% of the patients were operated by Ivanissevich, 22% received sclerotherapy. Sperm motility and morphological parameters were found subnormal. Taking into consideration relative subfertility of the patients, surgical results were positive. We continue follow-up of the patients and plan further studies of spermatogenesis.
The results of examination of 325 patients with chronic abacterial prostatitis, varicocele showed marked changes in ejaculate parameters of these patients. Prostatitis of different duration in the same degree causes pathozoospermia, reduces ejaculate fertility. Such condition of spermatogenesis indicates involvement of other sex organs suggested by the literature data and previous experience. This necessitates extended diagnostic examination of patients with chronic prostatitis.
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