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Biomedical subjects

V I Kandror

Publications and source records attributed to V I Kandror.

At least 19 recordsLinked to original sources

[Hypoglycemic effect of excess thyroid hormones in insulin deficiency].

In experiments on rats with severe streptozotocin diabetes, administration of high doses of L-thyroxine reduces hyperglycemia and glucosuria. It is postulated that glucose utilization by extrahepatic tissues does not depend on direct insulin action and that the Randle cycle is ineffective in hypermetabolism.

Animals

[Significance of beta-adrenoreception in realizing the glycogenolytic and lipolytic effects of excess thyroid hormones].

In experiments on rats the chronic administration of beta-adrenoblocker obsidan (propranolol) in doses blocking the glycogenolytic and lipolytic effects of exogenous epinephrine does not prevent a decrease in the liver and heart glycogen level and an increase of free fatty acids (FFA) in the serum as well as of lipolytic activity of adipose tissue in vitro, which are produced by high doses of thyroxine.

Adipose Tissue