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Biomedical subjects

V I Klimenko

Publications and source records attributed to V I Klimenko.

At least 19 recordsLinked to original sources
PubMed2004

[Modern tendencies of malignant pleural effusions epidemiology].

The during 7 years 258 patients with malignant effusion (ME) of different ethiology were treated in clinic, that composed 13.8% among all patients with pleural effusion. It was discovered the increase of this complication frequence in 1.6 time. The main reasons of ME were lung cancer--in 42.6% of observations, pleural mezothelioma--in 19.3%, mammary glands cancer--in 6.9%, real reason of ME was not found in 13.9%. Aged patients (oldest 60 years) are risk group for discovering of ME, for pleural mezothelioma the next ages are risk 30-40 and oldest 60 years.

Age Factors↗
PubMed2002

[Morphofunctional state of neutrophil granulocytes in Chernobyl nuclear plant accident clean-up workers with persistent leukopenia].

The obtained results of the analysis of the peripherical blood granulocytes morphofunctional condition in those persons who took part in the elimination of aftermaths of the Chernobyl accident, presenting with persistent leucopenia, suggest to us the presence of significant changes in morphological, cytochemical, and functional indices in the remote period.

Adult↗
PubMed2002

[Differential cytological diagnosis of pleural exudate].

Results of cytological investigation of pleural exudates were analyzed in 644 patients for the 2000-2000 yrs period. Meticulous description of principal kinds of pleural exudates is presented, differential signs of cytologic composition in patients with nonspecific, tuberculous, stagnant and oncologic pleuritis were delineated. The changes in cytological composition of exudates in lingering of the disease course are depicted. High diagnostic value of cytological investigation of pleural fluid, especially in presence of contraindications, was established.

Bacterial Infections↗
PubMed1999

[The indices of the peripheral blood leukocytes in subjects working within a 30-kilometer area of the Chernobyl Atomic Electric Power Station and in the workers of a chemical plant].

Changes in leukocytes are analyzed together with the pattern of leukogrammes, morphological and cytochemical parameters characterizing leukocytes of the peripheral blood in those persons working within the zone of radiation control and in workers of chemical plants. Criteria of high informative value have been established for identification of those groups of individuals running a risk for development of hematological pathology.

Adult↗
PubMed1998

[The characteristics of the bone marrow stromal elements in the participants in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station in the long term].

Histologic features were studied of bone marrow biopsies in 25 individuals who took part in the elimination of the aftermath of the Chernobyl accident and who had received a radiation dose of at least 1 Gy. Particular features of the studied trepanobiopsies included dysplasia of granulocytes, hypocellular bone marrow, circulatory disorders and sinusoidal distortion, edematization of stromal elements, substitution of fibroreticular tissue for hemopoietic one. No relationship was established between the changes revealed and radiation dose.

Biopsy↗
PubMed1991

[Clinico-immunocytological characteristics of leukemia in persons exposed to ionizing radiation effects due to the Chernobyl AES accident].

A total of 18 patients with acute leukemia from those exposed to radiation when they had liquidated the consequences of the accident at the Chernobyl Atomic Power Station were examined. Sixteen of them had acute myeloblast cell leukemia, one had acute lymphatic leukemia, and another one had acute promyelocytic leukemia. A complex of hematological, immunocytological, and cytochemical findings, as well as leukocytic and erythrocytic genetically determined antigen typing were used for diagnosis. Signs of severe vegetovascular dystonia was found to be followed by acute leukemia in all the patients. A relationship was established between the therapy resistance and the HLA antigen homozygosity in combination with genetically-determined low reactivity. There were no significant differences between the parameters in question and those in patients with acute leukemia who had been studied in the preaccident period.

Accidents↗