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Biomedical subjects

V I Korolev

Publications and source records attributed to V I Korolev.

At least 19 recordsLinked to original sources
PubMed2006

Mechanisms by which dolphins identify target movement characteristics and their technical use in hydrolocation and radiolocation.

The ability of the localizing system of the dolphin Tursiops truncatus to discriminate the dynamic characteristics of an object being located (a radially moving target) was studied. Measurements were made of the thresholds of the animals' sensitivity to the target speed (2.6 cm/sec) and acceleration (0.6 cm/sec(2)). For location of a target moving at constant speed, dolphins were found to use probe signals consisting of two impulses, while accelerating targets were located using probe signals consisting of three impulses. These characteristics were used to propose new and highly effective technical methods for hydrolocation and radiolocation.

Animals↗
PubMed2005

[Mechanisms of determining target locator velocity by dolphins and technical applications in hydrolocation and radiolocation].

Dolphin's (Tursiops truncatus) capacity to discriminate between dynamic characteristics of the object location (the target moving radially) was studied. The dolphin sensitivity thresholds for target velocity (2.6 cm/s) and for target acceleration (0.6 cm/s2) were measured. It has been shown that the animal emits two-pulse probe signal to locate the target moving with constant velocity, or three-pulse probe signal--to locate the accelerated target. New highly efficient technical methods of hydro- and radiolocation were suggested on the basis of these peculiarities.

Acoustics↗
PubMed2003

Results of primary reconstructions in patients with lesion of the tibial arteries.

An analysis was made of 146 primary reconstructions performed in 141 patients with occlusion of the arteries of the femoropopliteal segment and leg. At the hospital stage an improvement of the clinical status was attained after primary operations in 98% of cases. The five-year cumulative bypass patency after operations.accounted for 43.5% while the limbs could be saved in 91.5% of cases. The results obtained in patients with stage 2B chronic arterial ischemia (according to the A.V.Pokrovsky classification, 1979) coincided with the results of bypass grafts of the popliteal artery (the 5-year patency was 56.9% with the limbs saved in - 81.2% of cases), whereas the results of in situ vein bypass were marked by a significantly better cumulative patency in the long-term period.

Adult↗
PubMed1991

[Dosage loads on the bone marrow in exposure to ionizing radiation].

The authors made calculations of the expected dose loads on the bone marrow in the population of several regions due to the disaster release of radionuclides at the Chernobyl Atomic Station as well as in professional groups subjected to ionizing radiation, in particular, those working with radium light-compounds of permanent effect. The dose loads were largest in the population of the Byelorussian ecological region. Persons working in conditions of ionizing radiation showed a functional insufficiency of hemopoiesis in correspondence with the doses but there was no synchronicity in the responses of the bone marrow and peripheral blood.

Accidents↗
PubMed1991

[Bone marrow tissue doses in various types of radiation exposure].

Basing on some literature data and their own results, the authors calculated bone marrow radiation doses in global fallouts, medical x-ray investigations, a radionuclide fallout during the Chernobyl accident, and under occupational conditions during exposure to radiation factors of luminous compounds of permanent action (LCPA). Functional insufficiency of hemopoiesis and the absence of synchronization in bone marrow and peripheral blood responses to radiation exposure were revealed in professionals, working in contact with LCPA in correlation with doses of external inhomogeneous gamma-beam irradiation.

Accidents↗
PubMed1989

[The cellular sensitivity of the primary tumor and its metastases in breast cancer patients to cytostatics, interferon and tumor necrosis factor].

Samples of tumor tissue obtained from 47 patients with primary and metastatic breast cancer were implanted under the renal capsule of mice (SRCA-test) to assess individual sensitivity of these malignancies to cytostatics, recombinant interferon (rIFN) and--in some cases--to tumor necrosis factor (TNF). Primary tumor was shown to respond to cytostatics and rIFN in as few as 33.3 and 26.7% of cases, respectively. Xenografts of metastases displayed higher rates of response to all the drugs studied, viz. 64.2, 86.7 and 90% for cytostatics, rIFN and TNF, respectively.

Animals↗
PubMed1987

[Radioimmunologic analysis of ferritin, carcinoembryonic antigen and prolactin for evaluating the prognosis and effectiveness of treating breast cancer].

The levels of tumor markers--CEA, ferritin and prolactin (the hormone of the anterior pituitary gland) were studied in the blood serum of 178 breast cancer patients in the menopause during combined therapy using a radioimmunoassay. This combination was shown to be informative for assessment of prognosis of disease and efficacy of antitumor therapy which was confirmed by clinical and x-ray findings and observation of a tumor process in breast cancer patients over a 5-year period.

Biomarkers, Tumor↗