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Biomedical subjects

V I Pakhomov

Publications and source records attributed to V I Pakhomov.

At least 19 recordsLinked to original sources
PubMed1991

[Decrease of incidence of chromosome aberrations after a course of hyperbaric oxygenation].

The influence of the course of hyperbaric oxygenation (HBO) on the peripheral blood lymphocytes chromosomes of 7 patients with different pathology and of 3 healthy volunteers was studied. It is proved that after HBO course the frequency of chromosome, aberrations of chromatid type hasn't been practically changed whereas the frequency of aberrations of chromosome type significantly decreases by three times on the whole.

Cells, Cultured↗
PubMed1990

[The isolation of the contribution of the parenchyma to the radionephrogram and the assessment of kidney purifying function].

The authors described the principle and algorithms of the separation of a summary radionephrogram into constituents, reflecting the contribution of a radiopharmaceutical, uptaken by neutrons, and RP in the surrounding tissues. The authors proposed a correct method for estimation (using the first constituent) of the efficacy indicator of RP uptake by the kidneys (Q-parameter) and the indicator of the mean time of transit (t) in the kidneys of RP uptaken by their parenchyma. The results of testing of the proposed methods of Q and t calculation were presented. Values of these parameters were determined in health and in essential hypertension, I and II degree, pyelonephritis, chronic nephritis (latent and hypertensive types), stenosis of the renal artery, obstruction of the upper urinary tracts, and in one kidney. These results indicate the physiological adequacy of the employed mathematical models, proving the diagnostic informative value of the calculated indicators.

Humans↗
PubMed1990

[Hyperbaric oxygenation in neutralizing lipid peroxidation reactions and stabilizing cell membranes].

A study of the cardiac ejection, peripheral tissue oxygen utilization, changes of lipoprotein cholesterol concentration, radical and antioxidant activity of blood plasma under the effect of hyperbaric oxygenation revealed that hyperbaric oxygenation stabilizes the cell membranes increasing the functional capacities of cells and organs manifested in an enhancement of the oxidation-reduction processes in the tissues, increase of the cardiac ejection and initially reduced concentrations of high-density lipoprotein cholesterol.

Adult↗
PubMed1983

[Changes in cerebral hemodynamics in patients with vascular pathology in the late stages of radiation sickness treated with hyperbaric oxygenation].

Cerebral hemodynamic changes under hyperbaric oxygenation (HBO) were studied in 23 patients with brain vascular pathology in the late period of radiation-induced disease. The clinical improvement was observed in all the patients. The changes in hemodynamics and in neurological symptoms under HBO were not strictly mutually correlated.

Adult↗
PubMed1983

[Mathematical model of the kinetics of radiopharmaceutical preparations in the right compartments of the heart].

The paper is concerned with the description of a mathematical model of the kinetics of radiopharmaceutical drugs (RPD) in the right heart with due regard for its two-compartmental structure. A formula has been obtained to describe a right heart radiogram (RHRG) for any RPD entry into the heart (with any type of entry function). It has been shown that in case of an impulsed entry a RHRG curve is described by the following formula (formula; see text) which is a biexponential one. The above formula shows that the determination of phi 1 and phi 2 factor on a curve gives an opportunity to obtain exact information on the correlation of cardiac chamber volumes (the auricle and ventricle). The authors point a possibility of using a RHRG curve for the determination of cardiac output and rate. The formulas obtained are of particular value for analysis of the curves of radiocardiography with 133Xe.

Heart↗
PubMed1975

[Extracorporeal attachment of the allo-and xenokidneys to recipients' body for temporary decrease of the level of antibodies and complement activity].

Data given in our investigation put questions important for clinical aspects of transplantation on efficacy of perfusional immunosorption for subsequent kidney transplantation with a temporarily reduced level of preexistent antibodies, on the character of evolution of the secondary response under the same conditions, on the level of immunodepression required in treating such patients etc.

Antibodies↗