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Biomedical subjects

V I Sobolev

Publications and source records attributed to V I Sobolev.

At least 19 recordsLinked to original sources

[The influence of 2,4-dinitrophenol on the temperature effect of muscle contraction in experimental hyperthyroidism].

Experimental hyperthyroidism reduced the force of muscle contraction leaving unaltered the temperature of the contracting skeletal muscles in rats. The thermal effect therefore was increased as per the unit of developing force. Administration of 2,4-dinitrophenol increased the temperature effect in intact rats and exerted no influence in the hyperthyroid animals.

2,4-Dinitrophenol↗

[Angina morbidity in an organized collective with a periodic turnover of its personnel].

The article studies the average angina morbidity in the military unit during 9 years which resulted in 48.4% (scarlet fever--0.34%). Laboratory diagnostics is needed to make the estimation of streptococcal infection which has an acute respiratory infectious character during its clinical course. Among the whole number of patients 89.2% have come through this illness for one time, 9% twice, and 4.8%--three times. The dynamics of the angina morbidity had a periodical cycle of 2-3 years which was independent from the morbidity cycle of local civilian population. The authors show a statistic dependency between average morbidity index and the quantity of servicemen in one dormitory, its square and volume per one man. Application of "time before illness" index for 24 months made it possible to disclose the phase character in the development of streptococcal infection among personnel of the same call-up period. The general tendency towards reduction of the morbidity index was accompanied with regular upgrades of the infection after each spring or autumn renovation of personnel.

Adolescent↗

[The effect of triiodothyronine and catecholamines on the stability of trace effects of cold adaptation in rats].

The role of three-iodine-thyronine, noradrenaline (NA), adrenaline (A), reserpine and propranolol in extinguishing of trace-effects of the long-term cold adaptation was studied in rats. A possibility to control the process of the temperature disadaptation through administration of different hormonal drugs, was shown. Three-iodine-thyronine and NA proved to be the most effective in this respect. Weakening of sympathetic-adrenal effects by means of combined reserpine and propranolol during the disadaptation accelerated the process of extinguishing of practically all the trace-effects of the long-term cold adaptation.

Adaptation, Physiological↗