[The role of interrelationship of neutrophils, endotheliocytes and macrophages in the etiology and course of septic-purulent state. Report 4. Intercellular interaction in inflammation].
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Biomedical subjects
Publications and source records attributed to V I Zubkov.
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The results of comparative analysis of hemodynamic changes in patients of both groups with hypertonic and ischemic diseases of the heart were expounded. In these patients there were applied different methods of anesthesia during performance of reconstructive operation on aorta and vessels of lower extremities: in 66 of them (1 group) operation was performed in condition of endotracheal narcosis with neuroleptanalgesia, in 56 (2 group)--the prolonged epidural anesthesia. Stability of hemodynamics in perioperative period and lesser frequency of surgical and cardiological complications had allowed to recommend epidural anesthesia during performance of such operations.
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In 70 patients the course of infected forms of necrotic pancreatitis was analyzed. Severity degree of the patients conditions was estimated according to APACHE II scale. Practical recommendations about management of such patients were elaborated.
The infectionized necrotic pancreatitis (NP) course, complicated by localized and diffusive peritonitis, abscess and retroperitoneal phlegmon in 86 patients, was analyzed. Severity of state of patients according to the APACHE II scale was estimated. Recommendations for application of empirical and purposeful antibacterial therapy was elaborated. Total mortality for infectionized NP with complicated course was 25.5%.
In 22 patients with purulent-septic complications the extracorporal attaching of the xenolien cryopreserved sections was applied together with conventional therapy. Distinct reduction of the endogenic intoxication severity an the immune state of patients normalization were noted.
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The authors discuss the experience of using the spheric carbon hemosorbent for extracorporal hemoperfusion of blood in 12 patients with hepatic insufficiency developed against the background of obturation of the common bile duct by a stone or tumor. Positive clinical effects of hemosorption are shown. The method is recommended for the treatment of patients with hepatic insufficiency.
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