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Biomedical subjects

V Ia Plotkin

Publications and source records attributed to V Ia Plotkin.

At least 19 recordsLinked to original sources
PubMed1992

[The role of pharmacological tests in detecting disorders in the bronchial patency and bronchial reactivity of patients with chronic glomerulonephritis].

Data are reported of a study of the effect of atrovent, salbutamol and acetylcholine on bronchial patency and reactivity of the bronchi in 89 patients with glomerulonephritis (age: 17-49 years) with normal renal function and at the stage of chronic renal failure. The tests proved highly informative. Latent bronchospasm was found in 12.1% of patients with chronic glomerulonephritis. In 76.3% of patients at the stage of chronic renal failure hyperreactivity of the bronchi was found. The revealed changes require early diagnosis and treatment.

Acetylcholine↗
PubMed1991

[Effect of a single overheating on kidney ultrastructure].

Large human populations have to live and work under conditions of heat in the arid zones or in industry. It is shown in the experiment, that a single overheating of animals of various duration results in a considerable damage of glomeruli and tubules the clinical manifestation of which is the development of acute renal failure.

Acute Kidney Injury↗
PubMed1989

[Clinico-morphologic comparisons in mesangiocapillary glomerulonephritis].

Clinical, morphological and immunological examination was carried out in 146 patients with mesangiocapillary glomerulonephritis. The differences in the clinical manifestations of the disease were not significant. The lobular variant was more frequently distinguished by microhematuria, increased level of creatine and reduction of the blood serum complement. Morphological examination showed a significant increase of the mesangial matrix in the center of glomerular lobules.

Adolescent↗
PubMed1988

[One of the possible mechanisms of development and progression of chronic glomerulonephritis].

Proceeding from clinical examination of 430 patients with chronic glomerulonephritis (GN) and morphological, histochemical and biochemical studies on kidney biopsy specimens the author has proposed and substantiated a hypothesis, according to which prolonged raised protein reabsorption in cells of the proximal tubules (PT) of the kidney can cause breakage and distortion of the activity of transport systems responsible for the absorption and catabolism of macromolecules. These changes can result in PT cell breakage, escape of lysosomal enzymes into the lumen and basal membrane of PT cells and pericanalicular interstice with further development of cortical interstitial sclerosis. The combination of the above mentioned disturbances would lead to GN progression and development of renal insufficiency.

Atrophy↗
PubMed1986

[Nephrotic syndrome in primary glomerulonephritis].

The authors provide the clinico-morphological data obtained in 189 patients with primary glomerulonephritis (GN). The disease was manifested clinically by the nephrotic syndrome (NS). The NS was most commonly induced by membranous-proliferative GN (MPGN), membranous GN (MGN), diffuse mesangio-proliferative GN and focal segmental glomerulosclerosis (FSGS), accounting for 31, 25, 22.8 and 8.7% of cases, respectively. Hypertension together with edema was among the most common symptoms of the NS in adult patients. Functional disorders of the kidneys recorded in FSGS, MPGN and MGN patients were more significant as compared to those in other patients. The morphological findings alone, obtained with the aid of light, immunofluorescent and electron microscopy, play the key role in the diagnosis of different patterns of GN.

Adult↗