PubMed Health⌕ Search

Biomedical subjects

V Ito

Publications and source records attributed to V Ito.

5 recordsLinked to original sources
PubMed1998

Relationship between stress, coping, and postconcussion symptoms in a healthy adult population.

Study 1 examined the association between intensity of postconcussive symptoms (PCS), impact of daily stress, and level of perceived stress over the past month in a group of healthy young adults. There was a significant relationship between intensity of PCS and impact of daily stress, as well as level of perceived stress over the past month, independent of the frequency of stressful events experienced. Study 2 assessed the stability of the relationship between PCS and stress. Subjects rated intensity of PCS, impact of daily stress, and level of perceived stress on two separate occasions approximately 1 month apart. The Perceived Stress Scale demonstrated high test-retest reliability. Significant relationships were again found between intensity of PCS and level of perceived stress at both time points, independent of the frequency of stressful events. These results suggest that persistent symptoms in some individuals with postconcussive syndrome may be due, at least in part, to individual differences in the perceived stress of incurring a mild traumatic brain injury.

Journal Article↗
PubMed1993

Amantadine-induced coma.

Amantadine has found use primarily as an antiviral agent and in the symptomatic treatment of parkinsonism. However, the use of amantadine for the subjective alleviation of fatigue in multiple sclerosis and in the treatment of agitated aggressive behavior in the traumatic brain injured patient has also been described. Side effects of amantadine are primarily related to the central nervous system and include hallucinations, confusion, and nightmares. Toxic manifestations include acute psychosis, coma, cardiovascular toxicity, and death. Amantadine toxicity is a particular problem in patients with renal insufficiency because 90% of an oral dose is excreted unchanged in the urine. We present a case of amantadine-induced coma in a patient with multiple sclerosis and end-stage renal disease. Moreover, this degree of amantadine toxicity was profoundly apparent at a drug level usually not associated with such a severe presentation.

Adult↗
PubMed1993

Multichannel cochlear implantation in the rehabilitation of post-traumatic sensorineural hearing loss.

Although there is a 17% to 56% incidence of sensorineural hearing loss following head injury, to our knowledge cochlear implants have not been used in treatment of this problem in patients with cognitive deficits and aphasia. We report our experience with multichannel cochlear implantation in one such patient. The patient is a 26-year-old man with bitemporal lobe damage and T-11 paraplegia. The clinical profile showed emotional lability, perseveration of thought, impulsivity, good visuospatial orientation, and adequate use of oral and written language in conveying basic needs. Audiologic evaluation showed profound sensorineural hearing loss. Middle latency responses suggested intact thalamocortical pathways. The patient was provided with a multichannel cochlear implant with improvement in his speech recognition and functional skills. We conclude that the cochlear implant should be considered in patients with traumatic sensorineural hearing loss with relatively intact cognitive skills.

Adult↗
PubMed1977

Affinity of Sendai virus for the inner ear of mice.

The direct immunofluorescent antibody method revealed that Sendai virus, which was thought to be most prevalent in respiratory diseases in mice, infected the inner ear of mice when the virus was injected intracerebrally. Specific immunofluorescence that indicated the presence of antigens of Sendai virus was observed in both perilymphatic and endolymphatic structures. The routes of virus spread are discussed. This experimental study, using newborn mice and Sendai virus, may be useful for the investigation of the pathogenesis of viral labyrinthitis not only because of the high frequency of inner ear infection, but also because of long-time survivors which facilitate prolonged observation.

Animals↗