[Morphology of cardiovascular collapse during surgery].
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Biomedical subjects
Publications and source records attributed to V Iu Ostrovskiĭ.
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On the basis of a clinico-morphological analysis of 50 cases with acute respiratory viral infections, developing clinically with brain symptoms, the authors distinguish 2 main factors, influencing their development. The main factors consist in a evicious circles of respiratory disorders which causes the appearance of toxico-hypoxic encephalopathy. Encephalitis of an immuno-allergic nature are seen less frequently and may appear soon after acute respiratory viral infections. Histologically there are 2 forms of allergic encephalitis: 1) with perivascular lymphocyte infiltration and 2) hemorrhagical. The second form differs clinically from the first by apoplectic-like development with a coma and rapid short course. Both forms of poctinfluenza allergic encephalitis differ from encephalopathy in the fact that they develop not during the crucial phase of acute respiratory infection, but follow 1-2 weeks. The morphological differences of hemmorrhagical forms of poctinfluenza allergic encephalitis from from encephalopathy are characterized by intensive perivascular hemorrhages with a tendency towards their fusion; by changes in the vascular walls; by an appearance of small foci of colliquative necrosis and demyelinization.
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In 112 patients mathematical analysis of the cardiac rhythm indices and a biochemical investigation were effected during operative interventions with diverse types of endotracheal anesthesia. The correlation analysis of the cardiac rhythm parameters showed that at the most traumatic moment of the operation the synchronization of the functional links aimed at maintaining homeostasis was going up. Pharmacological block of adrenergic receptors results in weakening correlational interlinks. By analyzing the degree of synchronization marking functional links of the cardiac rhythm parameters that characterize the vegetative homeostasis it becomes possible to obtain information as to the level of the level of the adaptive-regulatory mechanisms tension and the correspondence of the depth of anesthesia to the seriousness of the operation trauma at different stages of surgery.
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The study was conducted in 58 patients with congenital heart diseases. Preoperative cardiac insufficiency in patients with congenital heart diseases was shown to favour a complicated postoperative course which, in turn, is accompanied by alterations in the water-electrolyte metabolism. The development of cellular hyperhydration in patients with congenital heart diseases depends on the severity of the postoperative course and is its characteristic reflection. Distinct changes in the content of the electrolytes develop at this stage: potassium concentration reduction in the cells and sodium concentration increase in them.
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Amino acid fund has been studied during complex therapy of 25 patients with sepsis. In 15 patients complex therapy included detoxicating hemosorption (3-5 sessions), in 10 patients hemosorption was supplemented by ultraviolet blood irradiation (5-10 sessions). Complex therapy employing hemosorption led to a decrease in serine plasma level. Changes in the amino acid fund of the whole blood were insignificant. Leucine, isoleucine, threonine and phenylalanine blood levels were significantly increased. The introduction of ultraviolet blood irradiation into complex therapy of patients reduced traumatic effect of sorption detoxication on blood cells and enhanced detoxicating effect.