Biomedical subjects

V Iu Tanchuk

Publications and source records attributed to V Iu Tanchuk.

2 recordsLinked to original sources

PubMed1995

[Evolutionary programming for finding "structure-activity" relationships in a series of 3-phenoxychromone and 3-phenoxy-4-hydroxycoumarin derivatives].

Based on a set of compounds possessing hypolipidemic activity, it was demonstrated that evolutionary algorithms can be successfully used to compile an informative set of molecular parameters. The parameter sets selected using the method of potential functions allowed correct prediction of the activity of test molecules.

4-Hydroxycoumarins↗

PubMedDate not supplied

[Common properties of pharmacological agonists and antagonists of surface membrane receptors].

Using experimental transcription model in vitro, and method of electron-topological calculations the elements of pharmacological and structural community have been found in the groups of physiologically active compounds (PAC), blocking and activating external cellular receptors. This finding confirms the necessity of subdivision special groups of bio-substrates blockators and activators for hierarchical classification, of PAC.

Animals↗