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Biomedical subjects

V J Sutton

Publications and source records attributed to V J Sutton.

2 recordsLinked to original sources

Superior rectus recessions for dissociated vertical deviation.

Thirty-two eyes of 31 patients received superior rectus recessions for the treatment of dissociated vertical deviation (DVD). All patients were followed for a postoperative period of at least six months, and 50% were followed for a period of three years or more. The differential diagnosis of DVD and inferior oblique overaction was important, and the distinguishing features of each are mentioned. A distinction was made between occlusion hyperphoria, a latent deviation in the preferred fixating eye, and DVD, a manifest deviation in the nonpreferred eye. In the vast majority of cases, a unilateral superior rectus recession of graduated amounts was performed in the eye with a cosmetically unacceptable DVD. The surgical "hang loose" technique permitted avoiding technically difficult situations. After operation 82% of the eyes were aligned, within the good to excellent categories (0-9 prism diopters).

Adolescent↗

Equivalence of microbiological and hydroxylamine methods of analysis for ampicillin dosage forms.

Ampicillin formulations were assayed by microbiological and hydroxylamine methods to determine whether thehydroxylamine analytical method is a suitable substitute for the microbiological method. Paired assay results by the 2 analytical methods were obtained on different strengths of tablet, capsule, and suspension, formulations containing ampicillin and ampicillin degradation compounds. Several statistical tests were used to assess the equivalence of the paired assay results. The data analyses indicate that the hydroxylamine method is a suitable substitute for the microbiological method for potency assays and stability studies of ampicillin formulations. The hydroxylamine method yielded slightly higher assay results than the microbiological method for severely degraded formulations.

Ampicillin↗