Uterine rupture with the use of vaginal prostaglandin E2 suppositories.
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Abortion, Therapeutic↗
Biomedical subjects
V K Knutzen
Publications and source records attributed to V K Knutzen.
Primary adenocarcinoma of the vulva originating in misplaced cloacal tissue.
Primary adenocarcinomas of the vulva are rare tumors and usually arise from the Bartholin's gland. However, other potential sources of adenocarcinoma exist. A case is reported where it is believed that the source of the primary adenocarcinoma was a misplaced cloacal remnant. The method of treatment was by radical surgery and the prognosis is uncertain.
Adenocarcinoma↗
Colposcopy and selective biopsy in patients with abnormal cervical cytology.
Patients with atypical or positive findings on cervical cytology should be referred to a special colposcopy clinic as the next step in investigation. Colposcopy complements cytology, and when combined with selective biopsy of the worst-affected area allows a high level of diagnostic accuracy (90,7%). The necessity for diagnostic conization with its risks is markedly reduced. When all three modalities were used in combination, only 0,7% of invasive cancers were missed.
Adult↗
Complications and outcome of induced labour.
One thousand and twenty-two induced labours are reviewed retrospectively. The incidence of induction of labour differed significantly in the various ethnic groups. Hypertension was the major indication and labour was successfully induced in 95,4% of patients. One-fifth of induced labours ended in caesarean section. The major complications associated with induction, fetal distress, cephalopelvic disproportion and hypertonic uterine inertia, and preventable. The perinatal loss associated with induction is mainly due to factors not related to induction per se.
Ethnicity↗
Perinatal mortality in Cape Town.
Perinatal mortality in Cape Town has progressively decreased in all racial groups over the past 60 years. The perinatal mortality rate for Coloureds and Blacks, however, remains at 20 per 1 000 more than for Whites. While the stillbirth rate approximates the early neonatal death rate in Whites, the stillbirth rate for Coloureds and Blacks is double the rate for early neonatal deaths. Although there is a significantly higher early neonatal death rate for Coloureds and Blacks, the major component of perinatal loss is stillbirth and 80% of stillbirths occur before the onset of labour. Focus should be on the detection of the fetus at risk, with, perhaps, earlier intervention.
Black or African American↗
The relationship between maternal height and weight at booking and perinatal mortality.
In this study, more of the Coloured women weighed less than 45 kg and more of them were significantly shorter than Black and White women. The short (less than 149 cm) Coloureds had a high perinatal mortality, as did the thin Coloureds (less than 45 kg). The short, thin Coloured women had the highest perinatal mortality, and fetal loss in this group was associated with preterm delivery, stillbirths before labour and fetoplacental inadequacy. Maternal height is an indicator of nutrition in childhood and maternal weight an indicator of more recent nutrition. Weight gain in pregnancy is particularly important in short, thin individuals.
Black or African American↗
Hypertension in pregnancy and perinatal mortality.
The effect of various forms of hypertension on perinatal mortality has been investigated. Non-essential, non-proteinuric hypertension had relatively little effect on perinatal mortality, whereas essential and proteinuric forms of hypertension had a marked influence. Diastolic blood pressures of less than 110 mmHg did not influence perinatal mortality. Fetal loss from hypertensive disease was largely accounted for by fetoplacental inadequacy, accidental haemorrhage and preterm delivery. Management more suited to individual needs and induction of labour, once biological and lung maturity has been achieved, is advocated.
Adolescent↗
The reproductive efficiency of the Xhosa.
Four sociogeographical groups of Xhosa were studied to show differences in their reproductive efficiencies. The rural groups showed increased perinatal, infant and over-all death rates compared with the urban groups. The highest death rate in all groups was during the infant period. The infant mortality was about 25% among the rural groups and 10% among the urban groups.
Black or African American↗
Rheumatic heart disease diagnosed during pregnancy: a 30-year follow-up.
One hundred one patients originally diagnosed as having rheumatic heart disease (RHD) during the years 1945-1948 were reevaluated in 1975 to determine the natural history of the disease. Twenty patients (19.8%) showed no sign of RHD. Of the patients with confirmed RHD, 56 (70.0%) had their original lesion confirmed, while 23 (28.8%) had developed additional valvular involvement. Pure mitral stenosis resulted in significantly lower mortality than all other valvular lesions, and congestive heart failure was the leading cause of death. Nineteen patients underwent cardiac surgery; the mortality in this group (52.6%) was not significantly higher than that in the overall RHD group (38.8%). False diagnosis of RHD during pregnancy is common. A more thorough evaluation of the "cardiac murmur of pregnancy" is advocated.
Adult↗