[Morphogenesis of experimental emphysema induced by different circulation disorders in the lungs].
Pulmonary emphysema was reproduced in 126 rabbits by disorders of circulation in the pulmonary artery system with the development of pre- and postcapillary hypertension and hypovolemia of pulmonary circulation. Under conditions of pulmonary circulation hypertension changes in the lungs initially are of the compensatory-hypertrophic nature: hyperplasia and distention of capillaries, myoelastosis of respiratory bronchioles and closing plates of alveoli, hypertrophy of the muscle wall of arteries and veins. At later intervals (4--12 months), processes of atrophy, sclerosis and inflation develop in the lungs; changes in the lungs acquire the nature of emphysema. Anemia, parenchymal atrophy, sclerosis and inflation develop in the lungs due to a considerable reduction of circulation.