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Biomedical subjects

V K Podymov

Publications and source records attributed to V K Podymov.

At least 19 recordsLinked to original sources
PubMed1988

[Acetylation phenotype in patients with periodic disease].

Acetylation phenotype distribution (activity of N-acetyltransferase enzyme) was studied in 29 patients with periodical disease (PD), 73 healthy persons (Armenians), and 20 patients (also Armenians) suffering from epithelial coccygeal cysts. The results obtained indicated the prevalence of slow acetylation phenotype (67%) in the entire Armenian population. PD was characterized by slow acetylation type (28 of 29 patients had slow acetylation with a high frequency of very slow inactivators). The other hereditary pathology, also specific for Armenians (epithelial coccygeal cysts), was characterized by another type of acetylation--a rapid one. The role of slow acetylation as a genetic marker of PD was discussed.

Acetylation↗
PubMed1976

Morphological manifestations of functional changes in the hypothalamic-pituitary neurosecretory system and kidneys of rats after space flight.

Morphological examination of the hypothalamic-pituitary neurosecretory systen and kidneys of rats flown for 22 d and sacrificed 2 and 27 d postflight was carried out. By histological and histochemical methods, indications of increased activities of the hypothalamicpituitary neurosecretory system and the juxtaglomerular apparatus of kidneys were found. The changes were reversible and by the 27th postflight day returned to the normal. It is suggested that the changes in the above systems may be produced not only by flight effects but also by readaptation of animals to 1 g.

Animals↗
PubMedDate not supplied

[Study of the dynamic distribution of azafen in the organs and tissues by using direct fluorimetry].

A quantitative method of direct fluometry of the samples without any preliminary extraction of the preparation, devised by the authors helped demonstrate that after its intravenous administration the cyclic antidepressant azaphen rapidly penetrates via the blood-cerebral, blood-ophthalmic, placental and other blood-histological barrier and is then quickly eliminated from the organism.

Animals↗