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Biomedical subjects

V K Treskunov

Publications and source records attributed to V K Treskunov.

17 recordsLinked to original sources
PubMed1990

[Bronchoconstrictive and bronchodilating effects of acetylsalicylic acid in patients with bronchial asthma].

An aspirin test has been performed in 100 asthma patients. The response of the bronchi appeared contradictory: aspirin asthma on the one hand, and bronchodilatation on the other occurred in 31 and 28 patients, respectively; 41 patients appeared nonresponders. Maximum effect of the drug was noted in the small bronchi. Desensitization to aspirin and hemosorption reduced asthma patients sensitivity to nonsteroid antiinflammatory drugs.

Adolescent↗
PubMed1990

[The effect of the plasma of patients with asthma of physical effort on the energy state of the lymphocytes].

The effect of the plasma obtained before and after graded submaximal exercise was examined in 10 bronchial asthma patients with the syndrome of asthma of physical effort (APE) by means of fluorescent exploration using the cation probe 4-(p-demethylaminostyryl)-1-methylpyridinum and rat thymocytes as a test system. Four normal donors and five bronchial asthma patients without the APE syndrome were used as control. The plasma of patients with the APE syndrome, obtained after physical exercise, brought about a decrease of the number of fluorescent cells. In APE patients, the coefficient of the drop of thymocyte fluorescence amounted to 0.65 +/- 0.04, that in the control group to 1.1 +/- 0.08 (p less than 0.01). It is assumed that after physical exercise in the plasma of APE patients, there may occur factor depolarizing the membrane of thymocytes, which is likely to play a substantial role in the pathogenesis of the afterload bronchospasm.

Adult↗
PubMed1989

[Hemosorption in the treatment of aspirin-induced bronchial asthma].

Oral aspirin test was performed in 50 asthma patients. Of them 18 patients exhibited idiosyncrasy to the drug. All the patients were subjected to hemosorption. Subsequently, 16 patients achieved remission. The hemosorption resulted in reduction of tracheobronchial hypersensitivity, especially to PGE2 alpha. Phagocytosis and T-cell immunity returned to normal. Sixteen patients underwent aspirin desensitization which had a more potent action on the function of beta-adrenergic receptors of the smooth muscles of the bronchi. Complete desensitization in 3 patients was recorded only after 1-3 hemosorption sessions.

Adult↗
PubMed1985

[Characteristics of the clinical course and therapy of status asthmaticus].

The increase in the incidence of the status asthmaticus seen over the last years is caused by the growth of the prevalence and a graver course of bronchial asthma. In each specific case, the therapy should be strictly individualized and rest on the dynamic evaluation of the cardiorespiratory system. The majority of patients with a history of the status asthmaticus show a tendency toward its recurrence. The dispensary follow up of patients by means of the allergological rooms plays an important role in the prevention of the development of the status asthmaticus. The clinical manifestations of the status asthmaticus depend to a considerable degree on the previously applied treatment.

Asthma↗
PubMed1973

[Duodenitis].

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Duodenal Diseases↗