PubMed Health⌕ Search

Biomedical subjects

V K Vinayak

Publications and source records attributed to V K Vinayak.

At least 19 recordsLinked to original sources
PubMed1979

Effect of corticosteroid and irradiation on caecal amoebic infection in rats.

Albino rats (Wistar strain) were pretreated with corticosteroid, irradiation or both to study the effect on the outcome of amoebic infection given intracaecally. The number of animals with lesions amongst "treated" groups was not significantly different from that amongst untreated control animals (P greater than 0.05) but amoebic pathology was markedly exacerbated amongst the treated animals. It is thus thought that once the amoebic infection is established, amoebae become better established for penetration in the immuno-depressed host. The study further suggests that corticosteroid therapy could aggravate an otherwise sub-clinical amoebic infection in man.

Animals↗
PubMed1979

Immunoglobulins in serum and duodenal juice and peripheral blood lymphocyte subpopulations in patients with giardiasis.

Forty eight patients with symptomatic giardiasis and 22 apparently healthy matched controls without Giardia lamblia were studied with respect to the following variables--immunoglobulins (Igs) G, A and M in serum, IgA in duodenal juice and T and B in lymphocyte sub-populations. There were no differences observed between the two groups with regard to any of these variables except for serum IgG which was found to be higher in patients. It was concluded that endemic giardiasis has no immunodeficient basis and has nothing in common with the association of giardiasis, mal absorption and immunodeficiency reported from the West. Further, no change in these variables was observed when the tests were repeated after cure.

Adolescent↗
PubMed1978

Phospholipid composition of Dipylidium caninum.

The phospholipid composition of Dipylidium caninum has been studied. Chloroform-methanol-soluble fraction amounted to 2.4% and phospholipids to 0.5% of the wet weight of the parasite. Phosphatidyl choline and phosphatidyl ethanolamine represented the bulk of the phospholipids, whereas phosphatidyl serine, phosphatidyl inositol, lysolecithin and lysophosphatidyl ethanolamine were present in minor amounts. Sulfatides were also identified in this parasite.

Animals↗
PubMed1978

Visceral leishmaniasis masquerading as a nasopharyngeal tumour. Report of a case.

A 55-year-old male, a resident of a village in the foothills of the Himalayas in the north-western region of India, presented with a huge nasopharyngeal tumour but was subsequently found to be infected with Leishmania donovani, involving the nasopharyngeal tissue and the draining lymph nodes as well as a visceral infection.

Diagnosis, Differential↗
PubMed1978

The interaction between Entamoeba histolytica and Syphacia obvelata infection in mice.

Mice naturally infected with Syphacia obvelata were challenged intracaecally with Entamoeba histolytica trophozoites. They showed a higher level of amoebic infection than mice without worms. Mice with the heaviest Syphacia infection were the most susceptible to amoebic infection. It appears that a concomitant infection with helminthic parasites residing in the caecum alters the outcome of an amoebic infection.

Animals↗
PubMed1977

On the phospholipids of adult Ancylostoma caninum.

The phospholipid composition of Ancylostoma caninum has been examined. Phospholipids amounted to 0.9% of the wet weight of the parasite. Ethanolamine and choline containing lipids comprised about 76% of the total phospholipids. Lysolecithin, sphingomyelin, phosphatidyl inositol and phosphatidyl serine were present in minor amounts. Cerebrosides and sulfatides were also identified.

Ancylostoma↗
PubMed1977

Amebic granuloma--an experimental study.

The etiopathogenesis of granuloma formation in amebiasis is not known. An experimental study was carried out in 48 guinea pigs arranged into four groups, to assess the role of hypersensitivity in formation of amebic granuloma. Repeated intracecal inoculations of saline in Group I and mixed amebic and bacterial suspension in other groups were made. Animals in Group III were sensitized by amebic antigen and in Group IV by bacterial antigen before inoculations. Lesions produced in the amebic hypersensitive group of animals were notably different from those in other groups. A higher frequency of cecal ulceration and a significantly severe grade of cecal damage was seen in these animals. Extensive pericecal adhesions and marked thickening of the wall produced nodular lesions. Granulomas were formed with dense chronic inflammatory cell infiltration including fibroblasts.

Animals↗